Primary Cardiac Lymphoma: Lessons Learned from a Long Survivor

Primary cardiac lymphoma (PCL) is a rare neoplasm that involves the heart, pericardium, or both. Patients with PCL have median survival of approximately 7 months. We report a 63-year-old woman with PCL treated with chemoimmunotherapy but relapsed 7 years later. She received automated implantable car...

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Main Authors: Baljit Singh, Randy Ip, Ahmed Ibrahim Al-Rajjal, Zyad Kafri, Ayad Al-Katib, Tarik Hadid
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2016/7164829
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author Baljit Singh
Randy Ip
Ahmed Ibrahim Al-Rajjal
Zyad Kafri
Ayad Al-Katib
Tarik Hadid
author_facet Baljit Singh
Randy Ip
Ahmed Ibrahim Al-Rajjal
Zyad Kafri
Ayad Al-Katib
Tarik Hadid
author_sort Baljit Singh
collection DOAJ
description Primary cardiac lymphoma (PCL) is a rare neoplasm that involves the heart, pericardium, or both. Patients with PCL have median survival of approximately 7 months. We report a 63-year-old woman with PCL treated with chemoimmunotherapy but relapsed 7 years later. She received automated implantable cardioverter-defibrillator (AICD) prophylactically shortly after the diagnosis. She presented with a breast recidive 7 years after initial diagnosis and died of relapsed small cell lung cancer. As many patients with PCL die early in the disease course due to life-threatening arrhythmias, preemptive implantation of AICD may improve mortality and prevent early death. Chemoimmunotherapy is effective in inducing remission in patients with PCL. Late and unusual pattern of relapse may be more frequent in patients with PCL and should be explored further. This case presents one of the longest surviving patients with PCL reported in the literature.
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institution Kabale University
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series Case Reports in Cardiology
spelling doaj-art-7c1ee2a908fa406aba2a2555868cbbab2025-08-20T03:35:44ZengWileyCase Reports in Cardiology2090-64042090-64122016-01-01201610.1155/2016/71648297164829Primary Cardiac Lymphoma: Lessons Learned from a Long SurvivorBaljit Singh0Randy Ip1Ahmed Ibrahim Al-Rajjal2Zyad Kafri3Ayad Al-Katib4Tarik Hadid5Graduate Medical Education, St. John Hospital and Medical Center, Detroit, MI, USAGraduate Medical Education, St. John Macomb-Oakland Hospital, Detroit, MI, USAGraduate Medical Education, St. John Hospital and Medical Center, Detroit, MI, USAVan Elslander Cancer Center, Grosse Pointe Woods, MI, USAVan Elslander Cancer Center, Grosse Pointe Woods, MI, USAVan Elslander Cancer Center, Grosse Pointe Woods, MI, USAPrimary cardiac lymphoma (PCL) is a rare neoplasm that involves the heart, pericardium, or both. Patients with PCL have median survival of approximately 7 months. We report a 63-year-old woman with PCL treated with chemoimmunotherapy but relapsed 7 years later. She received automated implantable cardioverter-defibrillator (AICD) prophylactically shortly after the diagnosis. She presented with a breast recidive 7 years after initial diagnosis and died of relapsed small cell lung cancer. As many patients with PCL die early in the disease course due to life-threatening arrhythmias, preemptive implantation of AICD may improve mortality and prevent early death. Chemoimmunotherapy is effective in inducing remission in patients with PCL. Late and unusual pattern of relapse may be more frequent in patients with PCL and should be explored further. This case presents one of the longest surviving patients with PCL reported in the literature.http://dx.doi.org/10.1155/2016/7164829
spellingShingle Baljit Singh
Randy Ip
Ahmed Ibrahim Al-Rajjal
Zyad Kafri
Ayad Al-Katib
Tarik Hadid
Primary Cardiac Lymphoma: Lessons Learned from a Long Survivor
Case Reports in Cardiology
title Primary Cardiac Lymphoma: Lessons Learned from a Long Survivor
title_full Primary Cardiac Lymphoma: Lessons Learned from a Long Survivor
title_fullStr Primary Cardiac Lymphoma: Lessons Learned from a Long Survivor
title_full_unstemmed Primary Cardiac Lymphoma: Lessons Learned from a Long Survivor
title_short Primary Cardiac Lymphoma: Lessons Learned from a Long Survivor
title_sort primary cardiac lymphoma lessons learned from a long survivor
url http://dx.doi.org/10.1155/2016/7164829
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AT randyip primarycardiaclymphomalessonslearnedfromalongsurvivor
AT ahmedibrahimalrajjal primarycardiaclymphomalessonslearnedfromalongsurvivor
AT zyadkafri primarycardiaclymphomalessonslearnedfromalongsurvivor
AT ayadalkatib primarycardiaclymphomalessonslearnedfromalongsurvivor
AT tarikhadid primarycardiaclymphomalessonslearnedfromalongsurvivor