Genetic insights into psychotic major depressive disorder: bridging the mood-psychotic disorder spectrumResearch in context

Genetic insights into psychotic major depressive disorder: bridging the mood-psychotic disorder spectrumResearch in context

Summary: Background: Psychotic major depressive disorder (MDD), a subtype of MDD characterised by psychotic symptoms that occur exclusively during mood episode, is clinically significant yet underexplored genetically due to its rarity. This study comprehensively examines the genetic basis of psycho...

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Main Authors: Thuy-Dung Nguyen, Joeri J. Meijsen, Robert Sigström, Ralf Kuja-Halkola, Ying Xiong, Arvid Harder, Kaarina Kowalec, Joëlle A. Pasman, Carolina Scarpa, Elin Hörbeck, Lina Jonsson, Sara Hägg, Niamh Mullins, Kevin S. O’Connell, Christina Dalman, Dorte Helenius, Richard Zetterberg, Henrik Larsson, Paul Lichtenstein, Ole A. Andreassen, Thomas Werge, Alfonso Buil, Mikael Landén, Patrick F. Sullivan, Yi Lu
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:EBioMedicine
Subjects:
Psychotic major depressive disorder
Psychotic disorders
Genetic
Epidemiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425000209
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