MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTS
The article presents analysis of scientific literature of the last 20 years about medicamental immunosupression in early age pediatric liver recipients in view of immune response characteristics and immunosuppressive drugs pharmacokinetics in such patients. The modern concept of immunosuppressive th...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2012-09-01
|
| Series: | Вестник трансплантологии и искусственных органов |
| Subjects: | |
| Online Access: | https://journal.transpl.ru/vtio/article/view/194 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849242059301453824 |
|---|---|
| author | S. V. Gautier D. S. Mnatsakanyan |
| author_facet | S. V. Gautier D. S. Mnatsakanyan |
| author_sort | S. V. Gautier |
| collection | DOAJ |
| description | The article presents analysis of scientific literature of the last 20 years about medicamental immunosupression in early age pediatric liver recipients in view of immune response characteristics and immunosuppressive drugs pharmacokinetics in such patients. The modern concept of immunosuppressive therapy protocol choice in pedia- tric liver recipients depending on complications development (nephrotoxicity, arterial hypertension and neuroto- xicity, the high risk of infectious complications, post-transplant proliferative disorders, metabolic and cosmetic side effects) is presented. Different opportunities of early steroid withdrawal, calcineurin inhibitor minimization in pediatric liver allograft recipients are covered. |
| format | Article |
| id | doaj-art-7c10d95134194ceca568b33f6cfaf3d0 |
| institution | Kabale University |
| issn | 1995-1191 |
| language | Russian |
| publishDate | 2012-09-01 |
| publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
| record_format | Article |
| series | Вестник трансплантологии и искусственных органов |
| spelling | doaj-art-7c10d95134194ceca568b33f6cfaf3d02025-08-20T03:59:56ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912012-09-01143778210.15825/1995-1191-2012-3-77-82137MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTSS. V. Gautier0D. S. Mnatsakanyan1Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowThe article presents analysis of scientific literature of the last 20 years about medicamental immunosupression in early age pediatric liver recipients in view of immune response characteristics and immunosuppressive drugs pharmacokinetics in such patients. The modern concept of immunosuppressive therapy protocol choice in pedia- tric liver recipients depending on complications development (nephrotoxicity, arterial hypertension and neuroto- xicity, the high risk of infectious complications, post-transplant proliferative disorders, metabolic and cosmetic side effects) is presented. Different opportunities of early steroid withdrawal, calcineurin inhibitor minimization in pediatric liver allograft recipients are covered.https://journal.transpl.ru/vtio/article/view/194liver transplantationimmune responsecalcineurin inhibitor |
| spellingShingle | S. V. Gautier D. S. Mnatsakanyan MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTS Вестник трансплантологии и искусственных органов liver transplantation immune response calcineurin inhibitor |
| title | MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTS |
| title_full | MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTS |
| title_fullStr | MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTS |
| title_full_unstemmed | MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTS |
| title_short | MEDICAMENTAL IMMUNOSUPRESSION IN EARLY AGE PEDIATRIC LIVER RECIPIENTS |
| title_sort | medicamental immunosupression in early age pediatric liver recipients |
| topic | liver transplantation immune response calcineurin inhibitor |
| url | https://journal.transpl.ru/vtio/article/view/194 |
| work_keys_str_mv | AT svgautier medicamentalimmunosupressioninearlyagepediatricliverrecipients AT dsmnatsakanyan medicamentalimmunosupressioninearlyagepediatricliverrecipients |