Synthesis and Biological Evaluation of Coumarinyl Sydnone Derivatives

A novel series of compounds containing coumarinyl sydnone derivatives from 4-methyl-7-hydroxy-8-nitro coumarin were synthesized. The formed compounds have been evaluated by physical methods (melting point, thin layer chromatography, elemental analysis) and by spectral data (IR, 1H-NMR & 13C NMR)...

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Main Authors: Keshav C. Patel, Himanshu D. Patel
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2011/705856
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author Keshav C. Patel
Himanshu D. Patel
author_facet Keshav C. Patel
Himanshu D. Patel
author_sort Keshav C. Patel
collection DOAJ
description A novel series of compounds containing coumarinyl sydnone derivatives from 4-methyl-7-hydroxy-8-nitro coumarin were synthesized. The formed compounds have been evaluated by physical methods (melting point, thin layer chromatography, elemental analysis) and by spectral data (IR, 1H-NMR & 13C NMR). The antimicrobial evaluation of the compounds showed that some of them revealed promising antimicrobial activity.
format Article
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institution Kabale University
issn 0973-4945
2090-9810
language English
publishDate 2011-01-01
publisher Wiley
record_format Article
series E-Journal of Chemistry
spelling doaj-art-7c07fa8e87fc459db339db610075230b2025-02-03T01:03:42ZengWileyE-Journal of Chemistry0973-49452090-98102011-01-018111311810.1155/2011/705856Synthesis and Biological Evaluation of Coumarinyl Sydnone DerivativesKeshav C. Patel0Himanshu D. Patel1Department of Chemistry, Veer Narmad South Gujarat University, Surat-395 007, Gujarat, IndiaDepartment of Chemistry, Veer Narmad South Gujarat University, Surat-395 007, Gujarat, IndiaA novel series of compounds containing coumarinyl sydnone derivatives from 4-methyl-7-hydroxy-8-nitro coumarin were synthesized. The formed compounds have been evaluated by physical methods (melting point, thin layer chromatography, elemental analysis) and by spectral data (IR, 1H-NMR & 13C NMR). The antimicrobial evaluation of the compounds showed that some of them revealed promising antimicrobial activity.http://dx.doi.org/10.1155/2011/705856
spellingShingle Keshav C. Patel
Himanshu D. Patel
Synthesis and Biological Evaluation of Coumarinyl Sydnone Derivatives
E-Journal of Chemistry
title Synthesis and Biological Evaluation of Coumarinyl Sydnone Derivatives
title_full Synthesis and Biological Evaluation of Coumarinyl Sydnone Derivatives
title_fullStr Synthesis and Biological Evaluation of Coumarinyl Sydnone Derivatives
title_full_unstemmed Synthesis and Biological Evaluation of Coumarinyl Sydnone Derivatives
title_short Synthesis and Biological Evaluation of Coumarinyl Sydnone Derivatives
title_sort synthesis and biological evaluation of coumarinyl sydnone derivatives
url http://dx.doi.org/10.1155/2011/705856
work_keys_str_mv AT keshavcpatel synthesisandbiologicalevaluationofcoumarinylsydnonederivatives
AT himanshudpatel synthesisandbiologicalevaluationofcoumarinylsydnonederivatives