Recovery of Olfactory Function Induces Neuroplasticity Effects in Patients with Smell Loss
The plasticity of brain function, especially reorganization after stroke or sensory loss, has been investigated extensively. Based upon its special characteristics, the olfactory system allows the investigation of functional networks in patients with smell loss, as it holds the unique ability to be...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2014/140419 |
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| author | Kathrin Kollndorfer Ksenia Kowalczyk Elisabeth Hoche Christian A. Mueller Michael Pollak Siegfried Trattnig Veronika Schöpf |
| author_facet | Kathrin Kollndorfer Ksenia Kowalczyk Elisabeth Hoche Christian A. Mueller Michael Pollak Siegfried Trattnig Veronika Schöpf |
| author_sort | Kathrin Kollndorfer |
| collection | DOAJ |
| description | The plasticity of brain function, especially reorganization after stroke or sensory loss, has been investigated extensively. Based upon its special characteristics, the olfactory system allows the investigation of functional networks in patients with smell loss, as it holds the unique ability to be activated by the sensorimotor act of sniffing, without the presentation of an odor. In the present study, subjects with chronic peripheral smell loss and healthy controls were investigated using functional magnetic resonance imaging (fMRI) to compare functional networks in one of the major olfactory areas before and after an olfactory training program. Data analysis revealed that olfactory training induced alterations in functional connectivity networks. Thus, olfactory training is capable of inducing neural reorganization processes. Furthermore, these findings provide evidence for the underlying neural mechanisms of olfactory training. |
| format | Article |
| id | doaj-art-7bfc19507bd24dafaa9367a10ac0df0a |
| institution | OA Journals |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-7bfc19507bd24dafaa9367a10ac0df0a2025-08-20T02:06:53ZengWileyNeural Plasticity2090-59041687-54432014-01-01201410.1155/2014/140419140419Recovery of Olfactory Function Induces Neuroplasticity Effects in Patients with Smell LossKathrin Kollndorfer0Ksenia Kowalczyk1Elisabeth Hoche2Christian A. Mueller3Michael Pollak4Siegfried Trattnig5Veronika Schöpf6Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaDepartment of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaDepartment of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaDepartment of Otorhinolaryngology, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaDepartment of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaHigh-Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaDepartment of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaThe plasticity of brain function, especially reorganization after stroke or sensory loss, has been investigated extensively. Based upon its special characteristics, the olfactory system allows the investigation of functional networks in patients with smell loss, as it holds the unique ability to be activated by the sensorimotor act of sniffing, without the presentation of an odor. In the present study, subjects with chronic peripheral smell loss and healthy controls were investigated using functional magnetic resonance imaging (fMRI) to compare functional networks in one of the major olfactory areas before and after an olfactory training program. Data analysis revealed that olfactory training induced alterations in functional connectivity networks. Thus, olfactory training is capable of inducing neural reorganization processes. Furthermore, these findings provide evidence for the underlying neural mechanisms of olfactory training.http://dx.doi.org/10.1155/2014/140419 |
| spellingShingle | Kathrin Kollndorfer Ksenia Kowalczyk Elisabeth Hoche Christian A. Mueller Michael Pollak Siegfried Trattnig Veronika Schöpf Recovery of Olfactory Function Induces Neuroplasticity Effects in Patients with Smell Loss Neural Plasticity |
| title | Recovery of Olfactory Function Induces Neuroplasticity Effects in Patients with Smell Loss |
| title_full | Recovery of Olfactory Function Induces Neuroplasticity Effects in Patients with Smell Loss |
| title_fullStr | Recovery of Olfactory Function Induces Neuroplasticity Effects in Patients with Smell Loss |
| title_full_unstemmed | Recovery of Olfactory Function Induces Neuroplasticity Effects in Patients with Smell Loss |
| title_short | Recovery of Olfactory Function Induces Neuroplasticity Effects in Patients with Smell Loss |
| title_sort | recovery of olfactory function induces neuroplasticity effects in patients with smell loss |
| url | http://dx.doi.org/10.1155/2014/140419 |
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