Transcriptomic and metabolomic analyses reveal the spatial role of carnitine metabolism in the progression of hepatitis B virus cirrhosis to hepatocellular carcinoma

Transcriptomic and metabolomic analyses reveal the spatial role of carnitine metabolism in the progression of hepatitis B virus cirrhosis to hepatocellular carcinoma

IntroductionLiver cirrhosis (LC) and hepatocellular carcinoma (HCC) resulting from chronic hepatitis B virus (HBV) infection are major health concerns. Identifying critical biomarkers and molecular targets is needed for early diagnosis, prognosis, and therapy of these diseases.MethodsIn this study,...

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Bibliographic Details
Main Authors: Pengxiang Gao, Qiuping Liu, Ziye Luo, Wenjun Pu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Microbiology
Subjects:
hepatitis B virus
liver cirrhosis
hepatocellular carcinoma
transcriptomic
metabolomic
mass spectrometry imaging
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1461456/full
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