Systemic Vascular Function Is Associated with Muscular Power in Older Adults
Age-associated loss of muscular strength and muscular power is a critical determinant of loss of physical function and progression to disability in older adults. In this study, we examined the association of systemic vascular function and measures of muscle strength and power in older adults. Measur...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Journal of Aging Research |
| Online Access: | http://dx.doi.org/10.1155/2012/386387 |
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| author | Kevin S. Heffernan Angela Chalé Cynthia Hau Gregory J. Cloutier Edward M. Phillips Patrick Warner Heather Nickerson Kieran F. Reid Jeffrey T. Kuvin Roger A. Fielding |
| author_facet | Kevin S. Heffernan Angela Chalé Cynthia Hau Gregory J. Cloutier Edward M. Phillips Patrick Warner Heather Nickerson Kieran F. Reid Jeffrey T. Kuvin Roger A. Fielding |
| author_sort | Kevin S. Heffernan |
| collection | DOAJ |
| description | Age-associated loss of muscular strength and muscular power is a critical determinant of loss of physical function and progression to disability in older adults. In this study, we examined the association of systemic vascular function and measures of muscle strength and power in older adults. Measures of vascular endothelial function included brachial artery flow-mediated dilation (FMD) and the pulse wave amplitude reactive hyperemia index (PWA-RHI). Augmentation index (AIx) was taken as a measure of systemic vascular function related to arterial stiffness and wave reflection. Measures of muscular strength included one repetition maximum (1RM) for a bilateral leg press. Peak muscular power was measured during 5 repetitions performed as fast as possible for bilateral leg press at 40% 1RM. Muscular power was associated with brachial FMD (r=0.43, P<0.05), PWA-RHI (r=0.42, P<0.05), and AIx (r=−0.54, P<0.05). Muscular strength was not associated with any measure of vascular function. In conclusion, systemic vascular function is associated with lower-limb muscular power but not muscular strength in older adults. Whether loss of muscular power with aging contributes to systemic vascular deconditioning or vascular dysfunction contributes to decrements in muscular power remains to be determined. |
| format | Article |
| id | doaj-art-7bf666dc3e984f2a8e4aa21d6f095895 |
| institution | Kabale University |
| issn | 2090-2204 2090-2212 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Aging Research |
| spelling | doaj-art-7bf666dc3e984f2a8e4aa21d6f0958952025-02-03T01:00:57ZengWileyJournal of Aging Research2090-22042090-22122012-01-01201210.1155/2012/386387386387Systemic Vascular Function Is Associated with Muscular Power in Older AdultsKevin S. Heffernan0Angela Chalé1Cynthia Hau2Gregory J. Cloutier3Edward M. Phillips4Patrick Warner5Heather Nickerson6Kieran F. Reid7Jeffrey T. Kuvin8Roger A. Fielding9Human Performance Laboratory, Department of Exercise Science, Syracuse University, Syracuse, NY 13244, USANutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USANutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USANutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USANutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USAThe Vascular Function Study Group, Division of Cardiology and the Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA 02111, USAThe Vascular Function Study Group, Division of Cardiology and the Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA 02111, USANutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USAThe Vascular Function Study Group, Division of Cardiology and the Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA 02111, USANutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USAAge-associated loss of muscular strength and muscular power is a critical determinant of loss of physical function and progression to disability in older adults. In this study, we examined the association of systemic vascular function and measures of muscle strength and power in older adults. Measures of vascular endothelial function included brachial artery flow-mediated dilation (FMD) and the pulse wave amplitude reactive hyperemia index (PWA-RHI). Augmentation index (AIx) was taken as a measure of systemic vascular function related to arterial stiffness and wave reflection. Measures of muscular strength included one repetition maximum (1RM) for a bilateral leg press. Peak muscular power was measured during 5 repetitions performed as fast as possible for bilateral leg press at 40% 1RM. Muscular power was associated with brachial FMD (r=0.43, P<0.05), PWA-RHI (r=0.42, P<0.05), and AIx (r=−0.54, P<0.05). Muscular strength was not associated with any measure of vascular function. In conclusion, systemic vascular function is associated with lower-limb muscular power but not muscular strength in older adults. Whether loss of muscular power with aging contributes to systemic vascular deconditioning or vascular dysfunction contributes to decrements in muscular power remains to be determined.http://dx.doi.org/10.1155/2012/386387 |
| spellingShingle | Kevin S. Heffernan Angela Chalé Cynthia Hau Gregory J. Cloutier Edward M. Phillips Patrick Warner Heather Nickerson Kieran F. Reid Jeffrey T. Kuvin Roger A. Fielding Systemic Vascular Function Is Associated with Muscular Power in Older Adults Journal of Aging Research |
| title | Systemic Vascular Function Is Associated with Muscular Power in Older Adults |
| title_full | Systemic Vascular Function Is Associated with Muscular Power in Older Adults |
| title_fullStr | Systemic Vascular Function Is Associated with Muscular Power in Older Adults |
| title_full_unstemmed | Systemic Vascular Function Is Associated with Muscular Power in Older Adults |
| title_short | Systemic Vascular Function Is Associated with Muscular Power in Older Adults |
| title_sort | systemic vascular function is associated with muscular power in older adults |
| url | http://dx.doi.org/10.1155/2012/386387 |
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