Dexmedetomidine reduces in-hospital mortality in aneurysmal subarachnoid hemorrhage patients by modulating three key genes and inflammatory pathways: insights from clinical and bioinformatics analyses

Dexmedetomidine reduces in-hospital mortality in aneurysmal subarachnoid hemorrhage patients by modulating three key genes and inflammatory pathways: insights from clinical and bioinformatics analyses

BackgroundAneurysmal subarachnoid hemorrhage (aSAH) is a cerebrovascular disease with high mortality. Dexmedetomidine has a neuroprotective effect. This study aimed to explore the clinical and molecular association between dexmedetomidine and in-hospital mortality of aSAH.MethodsPatients with aSAH i...

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Bibliographic Details
Main Authors: Zhi-ang Li, Hong-cai Wang, Xue-wei Zhang, Li-hong Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Neurology
Subjects:
aneurysmal subarachnoid hemorrhage
dexmedetomidine
in-hospital mortality
inflammation
immune
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1554809/full
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