Cutaneous graft-versus-host reaction in a female patient a year after orthotopic liver transplantation: a case report and a review of literature

The paper provides a brief overview of the data available in the literature with the discussion of the basic principles of the diagnosis and treatment of a graft-versus-host reaction (GVHR). After orthotopic liver transplantation, the incidence of this complication is 1–3%, mortality is as high as 7...

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Main Authors: Yu. V. Skvortsova, O. D. Olisov, V. E. Syutkin, D. M. Konovalov, A. V. Chzhao
Format: Article
Language:English
Published: N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department 2018-08-01
Series:Трансплантология (Москва)
Subjects:
Online Access:https://www.jtransplantologiya.ru/jour/article/view/272
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author Yu. V. Skvortsova
O. D. Olisov
V. E. Syutkin
D. M. Konovalov
A. V. Chzhao
author_facet Yu. V. Skvortsova
O. D. Olisov
V. E. Syutkin
D. M. Konovalov
A. V. Chzhao
author_sort Yu. V. Skvortsova
collection DOAJ
description The paper provides a brief overview of the data available in the literature with the discussion of the basic principles of the diagnosis and treatment of a graft-versus-host reaction (GVHR). After orthotopic liver transplantation, the incidence of this complication is 1–3%, mortality is as high as 75%. The paper describes a case of GVHR after liver transplantation, the clinical picture of which shows a preponderance of skin manifestations. Timely diagnosis of this rare complication has allowed the patient to be effectively treated.
format Article
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institution Kabale University
issn 2074-0506
2542-0909
language English
publishDate 2018-08-01
publisher N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
record_format Article
series Трансплантология (Москва)
spelling doaj-art-7bee6ea87d2e4327b5be0202f48ce4fa2025-08-20T03:35:37ZengN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentТрансплантология (Москва)2074-05062542-09092018-08-0101616710.23873/2074-0506-2010-0-1-61-67261Cutaneous graft-versus-host reaction in a female patient a year after orthotopic liver transplantation: a case report and a review of literatureYu. V. Skvortsova0O. D. Olisov1V. E. Syutkin2D. M. Konovalov3A. V. Chzhao4Federal Research Clinical Center of Pediatric Hematology, Oncology, and Immunology; Russian Pediatric Clinical HospitalN.V. Sklifosovsky Research Institute of Emergency CareN.V. Sklifosovsky Research Institute of Emergency CareFederal Research Clinical Center of Pediatric Hematology, Oncology, and Immunology; Russian State Medical UniversityN.V. Sklifosovsky Research Institute of Emergency CareThe paper provides a brief overview of the data available in the literature with the discussion of the basic principles of the diagnosis and treatment of a graft-versus-host reaction (GVHR). After orthotopic liver transplantation, the incidence of this complication is 1–3%, mortality is as high as 75%. The paper describes a case of GVHR after liver transplantation, the clinical picture of which shows a preponderance of skin manifestations. Timely diagnosis of this rare complication has allowed the patient to be effectively treated.https://www.jtransplantologiya.ru/jour/article/view/272hepatic cirrhosisorthotopic liver transplantationgraft-versus-host reaction
spellingShingle Yu. V. Skvortsova
O. D. Olisov
V. E. Syutkin
D. M. Konovalov
A. V. Chzhao
Cutaneous graft-versus-host reaction in a female patient a year after orthotopic liver transplantation: a case report and a review of literature
Трансплантология (Москва)
hepatic cirrhosis
orthotopic liver transplantation
graft-versus-host reaction
title Cutaneous graft-versus-host reaction in a female patient a year after orthotopic liver transplantation: a case report and a review of literature
title_full Cutaneous graft-versus-host reaction in a female patient a year after orthotopic liver transplantation: a case report and a review of literature
title_fullStr Cutaneous graft-versus-host reaction in a female patient a year after orthotopic liver transplantation: a case report and a review of literature
title_full_unstemmed Cutaneous graft-versus-host reaction in a female patient a year after orthotopic liver transplantation: a case report and a review of literature
title_short Cutaneous graft-versus-host reaction in a female patient a year after orthotopic liver transplantation: a case report and a review of literature
title_sort cutaneous graft versus host reaction in a female patient a year after orthotopic liver transplantation a case report and a review of literature
topic hepatic cirrhosis
orthotopic liver transplantation
graft-versus-host reaction
url https://www.jtransplantologiya.ru/jour/article/view/272
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