Exploring the role of intestinal pathogenic bacteria in metronidazole-induced bone loss: focus on Klebsiella variicola

Abstract Antibiotic use is known to contribute to the development of osteoporosis, although the exact mechanisms remain poorly understood. Metronidazole (MET), a commonly prescribed antibiotic for treating anaerobic infections, has been linked to alterations in the gut microbiota (GM), which in turn...

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Bibliographic Details
Main Authors: Xia Chen, Hongming Li, Guang Wang, Zhenxing Wang, Yan Lv, Hui Xie, Sheng Zhu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Gut Pathogens
Subjects:
Online Access:https://doi.org/10.1186/s13099-025-00713-4
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