A light-controlled one-tube detection platform combining CRISPR-Cas12a and RPA: an innovative approach for rapid diagnosis of Acinetobacter baumannii

A light-controlled one-tube detection platform combining CRISPR-Cas12a and RPA: an innovative approach for rapid diagnosis of Acinetobacter baumannii

BackgroundAcinetobacter baumannii (A. baumannii) is a significant pathogen associated with nosocomial infections, predominantly affecting immunocompromised patients, and is linked to high mortality rates. To control infection rates, there is an urgent need for a diagnostic method that is cost-effect...

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Bibliographic Details
Main Authors: Zihan Zhou, Lele Pan, Shihua Luo, Jiangmei Ma, Baoyan Ren, Lina Liang, Xuebin Li, Guijiang Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
CRISPR/Cas12a
NPOM-dt
one-tube detection
POCT
Acinetobacter baumannii
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1663915/full
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