Elimination of hepatocyte‐derived DPP4 downregulates cardiac immune‐ and collagen‐related genes but does not alter cardiac function in aged male mice
Abstract The association between metabolic dysfunction–associated steatotic liver disease (MASLD) and cardiovascular disease is well characterized; however, the underlying mechanism is incompletely understood. Interestingly, hepatocyte‐specific silencing of dipeptidyl peptidase 4 (DPP4) prevents liv...
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| Main Authors: | Natasha A. Trzaskalski, Melissa M. Dann, Antonio Hanson, Branka Vulesevic, Evgenia Fadzeyeva, Natasha Jeraj, Ilka Lorenzen‐Schmidt, Rick Seymour, Erin E. Mulvihill |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-08-01
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| Series: | Physiological Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.14814/phy2.70453 |
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