Serial measurement of nitrite and xanthine oxidase (XO) to assess antimicrobial pharmacodynamics (PD) and treatment efficacy in urinary tract infections (UTIs): A proof-of-concept for personalized antimicrobial therapy

Introduction: UTI is a common indication for antimicrobial therapy. Biomarkers specific to the causative organism, such as nitrite, are often employed in UTI diagnosis through qualitative detection methods such as dipsticks. XO was found to be a highly sensitive predictor for UTIs, but limited data...

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Bibliographic Details
Main Authors: Mrs Ellen Stadler, Professor Danny O`Hare, Professor Alison Holmes, Dr Timothy Rawson
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:International Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971224007963
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