Micropapillary Variant of Urothelial Carcinoma

Micropapillary carcinoma (MPC) of urinary tract is an uncommon variant of urothelial carcinoma with significant diagnostic and prognostic implications. Though MPC shows characteristic microscopic features, there exists interobserver variability and also it needs to be differentiated from the metasta...

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Main Authors: Ghee Young Kwon, Jae Y. Ro
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Advances in Urology
Online Access:http://dx.doi.org/10.1155/2011/217153
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author Ghee Young Kwon
Jae Y. Ro
author_facet Ghee Young Kwon
Jae Y. Ro
author_sort Ghee Young Kwon
collection DOAJ
description Micropapillary carcinoma (MPC) of urinary tract is an uncommon variant of urothelial carcinoma with significant diagnostic and prognostic implications. Though MPC shows characteristic microscopic features, there exists interobserver variability and also it needs to be differentiated from the metastasis from other organs. The prognosis is generally poor, depending on the proportion of the micropapillary component in some reports. Early cystectomy in cases with only lamina propria invasion may be indicated according to recent studies. This review outlines the general features of this entity and briefly comments on the controversies and the recent development.
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spelling doaj-art-7bd87e60c0084c23b98319220905fa3f2025-08-20T02:06:57ZengWileyAdvances in Urology1687-63691687-63772011-01-01201110.1155/2011/217153217153Micropapillary Variant of Urothelial CarcinomaGhee Young Kwon0Jae Y. Ro1Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Republic of KoreaDepartment of Pathology, The Methodist Hospital, Weill Medical College of Cornell University, Houston, TX 77030, USAMicropapillary carcinoma (MPC) of urinary tract is an uncommon variant of urothelial carcinoma with significant diagnostic and prognostic implications. Though MPC shows characteristic microscopic features, there exists interobserver variability and also it needs to be differentiated from the metastasis from other organs. The prognosis is generally poor, depending on the proportion of the micropapillary component in some reports. Early cystectomy in cases with only lamina propria invasion may be indicated according to recent studies. This review outlines the general features of this entity and briefly comments on the controversies and the recent development.http://dx.doi.org/10.1155/2011/217153
spellingShingle Ghee Young Kwon
Jae Y. Ro
Micropapillary Variant of Urothelial Carcinoma
Advances in Urology
title Micropapillary Variant of Urothelial Carcinoma
title_full Micropapillary Variant of Urothelial Carcinoma
title_fullStr Micropapillary Variant of Urothelial Carcinoma
title_full_unstemmed Micropapillary Variant of Urothelial Carcinoma
title_short Micropapillary Variant of Urothelial Carcinoma
title_sort micropapillary variant of urothelial carcinoma
url http://dx.doi.org/10.1155/2011/217153
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AT jaeyro micropapillaryvariantofurothelialcarcinoma