Single-cycle, pseudotyped reporter influenza virus to facilitate evaluation of treatment strategies for avian influenza, Ebola and other highly infectious diseases in vivo

Single-cycle, pseudotyped reporter influenza virus to facilitate evaluation of treatment strategies for avian influenza, Ebola and other highly infectious diseases in vivo

The rapid spread of infectious diseases presents a significant global threat, with seasonal influenza viruses, leading to 290,000–650,000 deaths annually. Emerging high pathogenic influenza strains from animals such as H5N1 and H7N9 further exacerbates pandemic risks. While developing effective vacc...

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Bibliographic Details
Main Authors: Tiong Kit Tan, Pramila Rijal, Kuan-Ying A. Huang, Stephen C. Hyde, Deborah R. Gill, Alain R. Townsend
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
pandemic
influenza
in vivo imaging
bioluminescence
reporter virus
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1608074/full
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