Minimally invasive nephrectomy for inflammatory renal disease

Objective: Once chronic inflammatory renal disease (IRD) develops, it creates a severe peri-fibrotic process, which makes it a relative contraindication for minimally invasive surgery (MIS). Our objective is to show that laparoscopic nephrectomy (LN) is a surgical option in IRD with fewer complicati...

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Main Authors: Paula Andrea Peña, Lynda Torres-Castellanos, Germán Patiño, Stefanía Prada, Luis Gabriel Villarraga, Nicolás Fernández
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Asian Journal of Urology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214388219300943
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author Paula Andrea Peña
Lynda Torres-Castellanos
Germán Patiño
Stefanía Prada
Luis Gabriel Villarraga
Nicolás Fernández
author_facet Paula Andrea Peña
Lynda Torres-Castellanos
Germán Patiño
Stefanía Prada
Luis Gabriel Villarraga
Nicolás Fernández
author_sort Paula Andrea Peña
collection DOAJ
description Objective: Once chronic inflammatory renal disease (IRD) develops, it creates a severe peri-fibrotic process, which makes it a relative contraindication for minimally invasive surgery (MIS). Our objective is to show that laparoscopic nephrectomy (LN) is a surgical option in IRD with fewer complications and better outcomes. Methods: Retrospective review of patients who underwent a modified-surgical laparoscopic transperitoneal nephrectomy was performed. Data search included all operated patients between May 2013 and May 2018 that had a pathology result with any renal inflammatory condition (xanthogranulomatous pyelonephritis, chronic nephritis, and renal tuberculosis). We describe intra-operative variables such as operative time, blood loss, conversion rate, postoperative complications and length of hospital stay. Results: There were 51 patients who underwent laparoscopic nephrectomy with a confirmatory pathology report for IRD. We identified four (8%) major complications; three of them required transfusion and one conversion to open surgery. The mean operative time was 233±108 min. Mean estimated blood loss was 206±242 mL excluding the conversion cases and 281±423 mL including them. The mean length of hospital stay was 3.0±2.0 days. Conclusion: Laparoscopic nephrectomy for IRD can safely be done. It is a reproducible technique with low risks and complication rates. Our experience supports that releasing the kidney first and leaving the hilum for the end is a safe approach when vascular structures are embedded into a single block of inflammatory and scar tissue.
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spelling doaj-art-7bc98c1fb1504e21b3560e6047b05dc72025-08-20T03:48:41ZengElsevierAsian Journal of Urology2214-38822020-10-017434535010.1016/j.ajur.2019.09.002Minimally invasive nephrectomy for inflammatory renal diseasePaula Andrea Peña0Lynda Torres-Castellanos1Germán Patiño2Stefanía Prada3Luis Gabriel Villarraga4Nicolás Fernández5Pontificia Universidad Javeriana, School of Medicine, Bogotá D.C., ColombiaDepartment of Urology, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana, School of Medicine, Bogotá D.C., ColombiaDivision of Urology, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana, Bogotá D.C., ColombiaDepartment of Urology, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana, School of Medicine, Bogotá D.C., ColombiaDepartment of Urology, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana, School of Medicine, Bogotá D.C., ColombiaDivision of Urology, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana, School of Medicine, Bogotá D.C., Colombia; Department of Urology, Fundación Santa Fe de Bogotá, Colombia; Division of Urology, Hospital for SickKids, University of Toronto, Toronto, Canada; Corresponding author. Department of Urology, Hospital Universitario San Ignacio and Pontificia Universidad Javeriana, Bogotá D.C., Colombia.Objective: Once chronic inflammatory renal disease (IRD) develops, it creates a severe peri-fibrotic process, which makes it a relative contraindication for minimally invasive surgery (MIS). Our objective is to show that laparoscopic nephrectomy (LN) is a surgical option in IRD with fewer complications and better outcomes. Methods: Retrospective review of patients who underwent a modified-surgical laparoscopic transperitoneal nephrectomy was performed. Data search included all operated patients between May 2013 and May 2018 that had a pathology result with any renal inflammatory condition (xanthogranulomatous pyelonephritis, chronic nephritis, and renal tuberculosis). We describe intra-operative variables such as operative time, blood loss, conversion rate, postoperative complications and length of hospital stay. Results: There were 51 patients who underwent laparoscopic nephrectomy with a confirmatory pathology report for IRD. We identified four (8%) major complications; three of them required transfusion and one conversion to open surgery. The mean operative time was 233±108 min. Mean estimated blood loss was 206±242 mL excluding the conversion cases and 281±423 mL including them. The mean length of hospital stay was 3.0±2.0 days. Conclusion: Laparoscopic nephrectomy for IRD can safely be done. It is a reproducible technique with low risks and complication rates. Our experience supports that releasing the kidney first and leaving the hilum for the end is a safe approach when vascular structures are embedded into a single block of inflammatory and scar tissue.http://www.sciencedirect.com/science/article/pii/S2214388219300943InflammationKidney diseasesLaparoscopyMinimally invasive surgical proceduresNephrectomyNephritis
spellingShingle Paula Andrea Peña
Lynda Torres-Castellanos
Germán Patiño
Stefanía Prada
Luis Gabriel Villarraga
Nicolás Fernández
Minimally invasive nephrectomy for inflammatory renal disease
Asian Journal of Urology
Inflammation
Kidney diseases
Laparoscopy
Minimally invasive surgical procedures
Nephrectomy
Nephritis
title Minimally invasive nephrectomy for inflammatory renal disease
title_full Minimally invasive nephrectomy for inflammatory renal disease
title_fullStr Minimally invasive nephrectomy for inflammatory renal disease
title_full_unstemmed Minimally invasive nephrectomy for inflammatory renal disease
title_short Minimally invasive nephrectomy for inflammatory renal disease
title_sort minimally invasive nephrectomy for inflammatory renal disease
topic Inflammation
Kidney diseases
Laparoscopy
Minimally invasive surgical procedures
Nephrectomy
Nephritis
url http://www.sciencedirect.com/science/article/pii/S2214388219300943
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AT stefaniaprada minimallyinvasivenephrectomyforinflammatoryrenaldisease
AT luisgabrielvillarraga minimallyinvasivenephrectomyforinflammatoryrenaldisease
AT nicolasfernandez minimallyinvasivenephrectomyforinflammatoryrenaldisease