Hepatic arterial infusion chemotherapy with Folfox 4 regimen versus cisplatin and gemcitabine for locally advanced intrahepatic cholangiocarcinoma

Hepatic arterial infusion chemotherapy with Folfox 4 regimen versus cisplatin and gemcitabine for locally advanced intrahepatic cholangiocarcinoma

Abstract For locally advanced intrahepatic cholangiocarcinoma (ICC), the combination of cisplatin plus gemcitabine (CisGem) is the standard first-line treatment. However, the outcome remains unsatisfied with the median overall survival (OS) of 11.7 months. We aimed to compare the effect of CisGem re...

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Bibliographic Details
Main Authors: Lin Liu, Huanhuan Wang, Liang Sun, Yufang Liu, Yujing Zhang, Xutian Wang, Xin Zheng
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Hepatic arterial infusion chemotherapy
Intrahepatic cholangiocarcinoma
Folfox 4
Gemcitabine
Cisplatin
Online Access:https://doi.org/10.1038/s41598-025-09586-8
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