Intravascular large B-cell lymphoma with respiratory failure diagnosed by random skin biopsy: A case report
Intravascular large B-cell lymphoma (IVLBCL) typically involves nonspecific symptoms that complicate diagnosis. This report discusses the case of a 70-year-old man, who presented with dyspnea, fatigue, and weight loss that evolved into severe respiratory failure, diagnosed with IVLBCL via random ski...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Respiratory Medicine Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007124001382 |
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| author | Haruka Fujioka Kei Nakashima Yuka Uesugi Miki Nyui Naoki Inoshima Jun Hayashi Michinori Yoshimi Miho Katsumata Masahiro Masuzawa Hayato Usami Akane Ito Rikako Tabata Kosei Matsue |
| author_facet | Haruka Fujioka Kei Nakashima Yuka Uesugi Miki Nyui Naoki Inoshima Jun Hayashi Michinori Yoshimi Miho Katsumata Masahiro Masuzawa Hayato Usami Akane Ito Rikako Tabata Kosei Matsue |
| author_sort | Haruka Fujioka |
| collection | DOAJ |
| description | Intravascular large B-cell lymphoma (IVLBCL) typically involves nonspecific symptoms that complicate diagnosis. This report discusses the case of a 70-year-old man, who presented with dyspnea, fatigue, and weight loss that evolved into severe respiratory failure, diagnosed with IVLBCL via random skin biopsy. The initial improvement in respiratory symptoms was followed by coronavirus disease. Response to steroid therapy and elevated lactate dehydrogenase levels suggested IVLBCL, confirmed by a random skin biopsy. The combination chemotherapy of rituximab, cyclophosphamide, vincristine, doxorubicin, and prednisolone improved the respiratory condition. This case highlights the diagnostic challenges associated with IVLBCL and the crucial role of random skin biopsy. |
| format | Article |
| id | doaj-art-7bc1c23595f6493fb9a9537824d02e07 |
| institution | OA Journals |
| issn | 2213-0071 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj-art-7bc1c23595f6493fb9a9537824d02e072025-08-20T02:38:05ZengElsevierRespiratory Medicine Case Reports2213-00712024-01-015210211510.1016/j.rmcr.2024.102115Intravascular large B-cell lymphoma with respiratory failure diagnosed by random skin biopsy: A case reportHaruka Fujioka0Kei Nakashima1Yuka Uesugi2Miki Nyui3Naoki Inoshima4Jun Hayashi5Michinori Yoshimi6Miho Katsumata7Masahiro Masuzawa8Hayato Usami9Akane Ito10Rikako Tabata11Kosei Matsue12Department of Pulmonology, Kameda Medical Center, Chiba, JapanDepartment of Pulmonology, Kameda Medical Center, Chiba, Japan; Corresponding author. Department of Pulmonology, Kameda Medical Center, 929 Higashi-cho, Kamogawa, Chiba, 296-8602, Japan.Department of Hematology and Oncology, Kameda Medical Center, Chiba, Japan; Division of Hematology, Department of Medicine, Showa University School of Medicine, Tokyo, JapanDepartment of Pathology, Kameda Medical Center, Chiba, JapanDepartment of Pulmonology, Kameda Medical Center, Chiba, JapanDepartment of Pulmonology, Kameda Medical Center, Chiba, JapanDepartment of Pulmonology, Kameda Medical Center, Chiba, JapanDepartment of Diabetes and Endocrinology, Kameda Medical Center, Chiba, Japan; Department of Diabetes and Endocrinology, Nara Medical University, Nara, JapanDepartment of Diabetes and Endocrinology, Kameda Medical Center, Chiba, JapanDepartment of General Medicine, Kameda Medical Center, Chiba, JapanDepartment of General Medicine, Kameda Medical Center, Chiba, JapanDepartment of Hematology and Oncology, Kameda Medical Center, Chiba, JapanDepartment of Hematology and Oncology, Kameda Medical Center, Chiba, JapanIntravascular large B-cell lymphoma (IVLBCL) typically involves nonspecific symptoms that complicate diagnosis. This report discusses the case of a 70-year-old man, who presented with dyspnea, fatigue, and weight loss that evolved into severe respiratory failure, diagnosed with IVLBCL via random skin biopsy. The initial improvement in respiratory symptoms was followed by coronavirus disease. Response to steroid therapy and elevated lactate dehydrogenase levels suggested IVLBCL, confirmed by a random skin biopsy. The combination chemotherapy of rituximab, cyclophosphamide, vincristine, doxorubicin, and prednisolone improved the respiratory condition. This case highlights the diagnostic challenges associated with IVLBCL and the crucial role of random skin biopsy.http://www.sciencedirect.com/science/article/pii/S2213007124001382Intravascular large B-Cell lymphomaRespiratory failureRandom skin biopsy |
| spellingShingle | Haruka Fujioka Kei Nakashima Yuka Uesugi Miki Nyui Naoki Inoshima Jun Hayashi Michinori Yoshimi Miho Katsumata Masahiro Masuzawa Hayato Usami Akane Ito Rikako Tabata Kosei Matsue Intravascular large B-cell lymphoma with respiratory failure diagnosed by random skin biopsy: A case report Respiratory Medicine Case Reports Intravascular large B-Cell lymphoma Respiratory failure Random skin biopsy |
| title | Intravascular large B-cell lymphoma with respiratory failure diagnosed by random skin biopsy: A case report |
| title_full | Intravascular large B-cell lymphoma with respiratory failure diagnosed by random skin biopsy: A case report |
| title_fullStr | Intravascular large B-cell lymphoma with respiratory failure diagnosed by random skin biopsy: A case report |
| title_full_unstemmed | Intravascular large B-cell lymphoma with respiratory failure diagnosed by random skin biopsy: A case report |
| title_short | Intravascular large B-cell lymphoma with respiratory failure diagnosed by random skin biopsy: A case report |
| title_sort | intravascular large b cell lymphoma with respiratory failure diagnosed by random skin biopsy a case report |
| topic | Intravascular large B-Cell lymphoma Respiratory failure Random skin biopsy |
| url | http://www.sciencedirect.com/science/article/pii/S2213007124001382 |
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