Causal Link between Ventricular Ectopy and Concussion
We present a unique case study report of a male individual with a history of mild nonischaemic cardiomyopathy, with no ventricular ectopy, that at the age of 76 years sustained multiple concussions (i.e., mild traumatic brain injury) within a week of each other. Concussion symptoms included cognitiv...
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| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2020/7154120 |
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| author | J. Patrick Neary Jyotpal Singh Jonathan P. Christiansen Taylor A. Teckchandani Kirsty L. Potter |
| author_facet | J. Patrick Neary Jyotpal Singh Jonathan P. Christiansen Taylor A. Teckchandani Kirsty L. Potter |
| author_sort | J. Patrick Neary |
| collection | DOAJ |
| description | We present a unique case study report of a male individual with a history of mild nonischaemic cardiomyopathy, with no ventricular ectopy, that at the age of 76 years sustained multiple concussions (i.e., mild traumatic brain injury) within a week of each other. Concussion symptoms included cognitive difficulties, “not feeling well,” lethargy, fatigue, and signs of depression. He was later medically diagnosed with postconcussion syndrome. The patient, WJT, was referred for cardiac and neurological assessment. Structural neuroimaging of the brain (MRI) was unremarkable, but electrocardiography (ECG) assessments using a 24-hour Holter monitor revealed significant incidence of ventricular ectopy (9.4%; 9,350/99,836 beats) over a period of 5–6 months after injury and then a further increase in ventricular ectopy to 18% (15,968/88,189 beats) during the subsequent 3 months. The patient was then prescribed Amiodarone 200 mg, and his ventricular ectopy and concussion symptoms completely resolved simultaneously within days. To the authors’ knowledge, our study is the first to show a direct link between observable and documented cardiac dysregulation and concussion symptomology. Our study has important implications for both cardiac patients and the patients that sustain a concussion, and if medically managed with appropriate pharmacological intervention, it can reverse ventricular ectopy and concussion symptomology. More research is warranted to investigate the mechanisms for this dramatic and remarkable change in cardiac and cerebral functions and to further explore the brain-heart interaction and the intricate autonomic interaction that exists between the extrinsic and intracardiac nervous systems. |
| format | Article |
| id | doaj-art-7bc157f0437845d4827dab1c50975e89 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-7bc157f0437845d4827dab1c50975e892025-02-03T00:58:44ZengWileyCase Reports in Medicine1687-96271687-96352020-01-01202010.1155/2020/71541207154120Causal Link between Ventricular Ectopy and ConcussionJ. Patrick Neary0Jyotpal Singh1Jonathan P. Christiansen2Taylor A. Teckchandani3Kirsty L. Potter4Faculty of Kinesiology & Health Studies, University of Regina, 3737 Wascana Parkway, Regina, SK S4S 0A2, CanadaFaculty of Kinesiology & Health Studies, University of Regina, 3737 Wascana Parkway, Regina, SK S4S 0A2, CanadaUniversity of Auckland, Faculty of Medical and Health Sciences, 85 Park Road, Grafton, Auckland 1023, New ZealandFaculty of Kinesiology & Health Studies, University of Regina, 3737 Wascana Parkway, Regina, SK S4S 0A2, CanadaWaitemata Cardiology, 181 Shakespeare Road, Milford, Auckland 0620, New ZealandWe present a unique case study report of a male individual with a history of mild nonischaemic cardiomyopathy, with no ventricular ectopy, that at the age of 76 years sustained multiple concussions (i.e., mild traumatic brain injury) within a week of each other. Concussion symptoms included cognitive difficulties, “not feeling well,” lethargy, fatigue, and signs of depression. He was later medically diagnosed with postconcussion syndrome. The patient, WJT, was referred for cardiac and neurological assessment. Structural neuroimaging of the brain (MRI) was unremarkable, but electrocardiography (ECG) assessments using a 24-hour Holter monitor revealed significant incidence of ventricular ectopy (9.4%; 9,350/99,836 beats) over a period of 5–6 months after injury and then a further increase in ventricular ectopy to 18% (15,968/88,189 beats) during the subsequent 3 months. The patient was then prescribed Amiodarone 200 mg, and his ventricular ectopy and concussion symptoms completely resolved simultaneously within days. To the authors’ knowledge, our study is the first to show a direct link between observable and documented cardiac dysregulation and concussion symptomology. Our study has important implications for both cardiac patients and the patients that sustain a concussion, and if medically managed with appropriate pharmacological intervention, it can reverse ventricular ectopy and concussion symptomology. More research is warranted to investigate the mechanisms for this dramatic and remarkable change in cardiac and cerebral functions and to further explore the brain-heart interaction and the intricate autonomic interaction that exists between the extrinsic and intracardiac nervous systems.http://dx.doi.org/10.1155/2020/7154120 |
| spellingShingle | J. Patrick Neary Jyotpal Singh Jonathan P. Christiansen Taylor A. Teckchandani Kirsty L. Potter Causal Link between Ventricular Ectopy and Concussion Case Reports in Medicine |
| title | Causal Link between Ventricular Ectopy and Concussion |
| title_full | Causal Link between Ventricular Ectopy and Concussion |
| title_fullStr | Causal Link between Ventricular Ectopy and Concussion |
| title_full_unstemmed | Causal Link between Ventricular Ectopy and Concussion |
| title_short | Causal Link between Ventricular Ectopy and Concussion |
| title_sort | causal link between ventricular ectopy and concussion |
| url | http://dx.doi.org/10.1155/2020/7154120 |
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