Phyto-synthesis of silver nanoparticles from Plumeria pudica leaf extract and its application in anti-cancerous activity
In this study, we have developed an environment friendly and novel approach for the synthesis of silver nanoparticles utilising plumeria pudica leaf extract. In this technique, the leaf extract was employed as both a reducing agent for the reduction of a silver nitrate (AgNO3) solution and a capping...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Journal of Experimental Nanoscience |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/17458080.2023.2267183 |
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| author | Sumit K. Shrivastava Asita Kulshreshtha Rajesh K. Gangwar Shikha Srivastava Abhishek P. Tiwari Santpal Singh Saurabh Kumar Shama Parveen Monisha Banerjee Dhirendra K. Chaudhary |
| author_facet | Sumit K. Shrivastava Asita Kulshreshtha Rajesh K. Gangwar Shikha Srivastava Abhishek P. Tiwari Santpal Singh Saurabh Kumar Shama Parveen Monisha Banerjee Dhirendra K. Chaudhary |
| author_sort | Sumit K. Shrivastava |
| collection | DOAJ |
| description | In this study, we have developed an environment friendly and novel approach for the synthesis of silver nanoparticles utilising plumeria pudica leaf extract. In this technique, the leaf extract was employed as both a reducing agent for the reduction of a silver nitrate (AgNO3) solution and a capping agent, leading to the synthesis of silver nanoparticles (Ag NPs). The outcomes of these analyses revealed an average particle size of ∼19 nm as determined by SEM, while XRD measurements indicated a crystalline domain size of ∼12 nm and a lattice parameter of approximately 4.087467 Å. Furthermore, the anti-cancer potential of the synthesised silver nanoparticles was evaluated, unveiling an IC50 value of around 28 µM. This suggests that the introduced silver nanoparticles may have triggered apoptosis, consequently inducing cell death. These findings underscore the potential of utilising environmentally benign silver nanoparticles in lung cancer chemotherapy. |
| format | Article |
| id | doaj-art-7bc0a6df68e14f3f84f93d7f48d51218 |
| institution | OA Journals |
| issn | 1745-8080 1745-8099 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Experimental Nanoscience |
| spelling | doaj-art-7bc0a6df68e14f3f84f93d7f48d512182025-08-20T02:23:41ZengTaylor & Francis GroupJournal of Experimental Nanoscience1745-80801745-80992023-12-0118110.1080/17458080.2023.2267183Phyto-synthesis of silver nanoparticles from Plumeria pudica leaf extract and its application in anti-cancerous activitySumit K. Shrivastava0Asita Kulshreshtha1Rajesh K. Gangwar2Shikha Srivastava3Abhishek P. Tiwari4Santpal Singh5Saurabh Kumar6Shama Parveen7Monisha Banerjee8Dhirendra K. Chaudhary9Amity School of Applied Sciences Lucknow, Amity University U.P, Lucknow, UP, IndiaAmity School of Applied Sciences Lucknow, Amity University U.P, Lucknow, UP, IndiaCouncil of Science & Technology U.P., Lucknow, UP, IndiaDepartment of Electronics & Communication Engineering, Madan Mohan Malviya University of Technology, Gorakhpur, UP, IndiaDepartment of Physics, Babasaheb Bhimrao Ambedkar University, Lucknow, UP, IndiaAmity School of Applied Sciences Lucknow, Amity University U.P, Lucknow, UP, IndiaMolecular and Human Genetics laboratory, Department of Zoology, University of Lucknow, Lucknow, UP, IndiaMolecular and Human Genetics laboratory, Department of Zoology, University of Lucknow, Lucknow, UP, IndiaMolecular and Human Genetics laboratory, Department of Zoology, University of Lucknow, Lucknow, UP, IndiaCentre for Renewable Energy, Prof. Rajendra Singh (Rajju Bhaiya) Institute of Physical Sciences for Study and Research, V. B. S. Purvanchal University, Jaunpur, IndiaIn this study, we have developed an environment friendly and novel approach for the synthesis of silver nanoparticles utilising plumeria pudica leaf extract. In this technique, the leaf extract was employed as both a reducing agent for the reduction of a silver nitrate (AgNO3) solution and a capping agent, leading to the synthesis of silver nanoparticles (Ag NPs). The outcomes of these analyses revealed an average particle size of ∼19 nm as determined by SEM, while XRD measurements indicated a crystalline domain size of ∼12 nm and a lattice parameter of approximately 4.087467 Å. Furthermore, the anti-cancer potential of the synthesised silver nanoparticles was evaluated, unveiling an IC50 value of around 28 µM. This suggests that the introduced silver nanoparticles may have triggered apoptosis, consequently inducing cell death. These findings underscore the potential of utilising environmentally benign silver nanoparticles in lung cancer chemotherapy.https://www.tandfonline.com/doi/10.1080/17458080.2023.2267183IC50plumeria pudica leafgreen synthesiseco-friendlyanti-cancer activity |
| spellingShingle | Sumit K. Shrivastava Asita Kulshreshtha Rajesh K. Gangwar Shikha Srivastava Abhishek P. Tiwari Santpal Singh Saurabh Kumar Shama Parveen Monisha Banerjee Dhirendra K. Chaudhary Phyto-synthesis of silver nanoparticles from Plumeria pudica leaf extract and its application in anti-cancerous activity Journal of Experimental Nanoscience IC50 plumeria pudica leaf green synthesis eco-friendly anti-cancer activity |
| title | Phyto-synthesis of silver nanoparticles from Plumeria pudica leaf extract and its application in anti-cancerous activity |
| title_full | Phyto-synthesis of silver nanoparticles from Plumeria pudica leaf extract and its application in anti-cancerous activity |
| title_fullStr | Phyto-synthesis of silver nanoparticles from Plumeria pudica leaf extract and its application in anti-cancerous activity |
| title_full_unstemmed | Phyto-synthesis of silver nanoparticles from Plumeria pudica leaf extract and its application in anti-cancerous activity |
| title_short | Phyto-synthesis of silver nanoparticles from Plumeria pudica leaf extract and its application in anti-cancerous activity |
| title_sort | phyto synthesis of silver nanoparticles from plumeria pudica leaf extract and its application in anti cancerous activity |
| topic | IC50 plumeria pudica leaf green synthesis eco-friendly anti-cancer activity |
| url | https://www.tandfonline.com/doi/10.1080/17458080.2023.2267183 |
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