Gender specific influence of serotonin on core symptoms and neurodevelopment of autism spectrum disorders: A multicenter study in China

Gender specific influence of serotonin on core symptoms and neurodevelopment of autism spectrum disorders: A multicenter study in China

Abstract Background High serotonin (5-hydroxytryptamine [5-HT]) blood levels are the most reliable and frequently replicated biomarker for autism spectrum disorders (ASDs). However, their differential influence on core ASD symptoms in males and females remains unclear. This study aimed to investigat...

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Main Authors: Qiu-hong Mou, Qian Zhang, Li Chen, Ying Dai, Hua Wei, Fei-Yong Jia, Yan Hao, Ling Li, Jie Zhang, Li-Jie Wu, Xiao-Yan Ke, Ming-Ji Yi, Qi Hong, Jin-Jin Chen, Shuan-Feng Fang, Yi-Chao Wang, Qi Wang, Jie Chen, Ting-Yu Li, Ting Yang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Child and Adolescent Psychiatry and Mental Health
Subjects:
Autism spectrum disorder
5-HT
Neurological development
Clinical symptoms
Sex differences
Online Access:https://doi.org/10.1186/s13034-025-00892-7
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