Effect of transforming growth factor beta receptor I inhibitors on myotube formation in vitro

Abstract Skeletal muscle injury often occurs after trauma or reconstructive surgery. However, full muscle regeneration is often not achieved because of fibrosis. A key pathway in fibrosis is transforming growth factor ß (TGFß) signaling. Many small molecules that inhibit the TGFß receptor are invest...

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Bibliographic Details
Main Authors: Louise De Saeytyd, Zhihao Wang, Marjon Bloemen, Johannes W. Von den Hoff
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-09381-5
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