Echocardiogram: The GPS to GPA’s Heart (Granulomatosis with Polyangiitis)
Granulomatosis with polyangiitis (GPA) is a rare ANCA-associated necrotizing granulomatous vasculitis affecting small- to medium-sized vessels. Common manifestations of this disease process affect the ear, nose, throat, upper and lower airways, and kidneys. Cardiac involvement has been reported in 6...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2019/7609386 |
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| author | Manpreet K. Parmar Mariam Alikhan Vivien M. Hsu Amanda Borham |
| author_facet | Manpreet K. Parmar Mariam Alikhan Vivien M. Hsu Amanda Borham |
| author_sort | Manpreet K. Parmar |
| collection | DOAJ |
| description | Granulomatosis with polyangiitis (GPA) is a rare ANCA-associated necrotizing granulomatous vasculitis affecting small- to medium-sized vessels. Common manifestations of this disease process affect the ear, nose, throat, upper and lower airways, and kidneys. Cardiac involvement has been reported in 6–44% of patients, primarily as coronary arteritis and pericarditis. A majority of case reports of pericardial effusions in patients with GPA identify patients having constrictive pericarditis secondary to uremia. We are presenting a case of hemorrhagic pericarditis in a patient with GPA in which the underlying inflammatory vasculitis likely played the primary role in the patient’s presentation. Echocardiographic abnormalities have been found in 80% of patients with GPA. Given the high mortality from cardiac involvement in patients with GPA, screening echocardiograms for this patient population may serve as a helpful tool in gauging disease severity, thereby guiding therapy to prevent serious cardiac complications, such as cardiac tamponade as presented in this case report. |
| format | Article |
| id | doaj-art-7b9b5a40b15c4909898829ff8a8ba3b3 |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-7b9b5a40b15c4909898829ff8a8ba3b32025-08-20T03:35:02ZengWileyCase Reports in Rheumatology2090-68892090-68972019-01-01201910.1155/2019/76093867609386Echocardiogram: The GPS to GPA’s Heart (Granulomatosis with Polyangiitis)Manpreet K. Parmar0Mariam Alikhan1Vivien M. Hsu2Amanda Borham3Robert Wood Johnson Medical School, Piscataway Township, NJ, USARobert Wood Johnson Medical School, Piscataway Township, NJ, USARobert Wood Johnson Medical School, Piscataway Township, NJ, USARobert Wood Johnson Medical School, Piscataway Township, NJ, USAGranulomatosis with polyangiitis (GPA) is a rare ANCA-associated necrotizing granulomatous vasculitis affecting small- to medium-sized vessels. Common manifestations of this disease process affect the ear, nose, throat, upper and lower airways, and kidneys. Cardiac involvement has been reported in 6–44% of patients, primarily as coronary arteritis and pericarditis. A majority of case reports of pericardial effusions in patients with GPA identify patients having constrictive pericarditis secondary to uremia. We are presenting a case of hemorrhagic pericarditis in a patient with GPA in which the underlying inflammatory vasculitis likely played the primary role in the patient’s presentation. Echocardiographic abnormalities have been found in 80% of patients with GPA. Given the high mortality from cardiac involvement in patients with GPA, screening echocardiograms for this patient population may serve as a helpful tool in gauging disease severity, thereby guiding therapy to prevent serious cardiac complications, such as cardiac tamponade as presented in this case report.http://dx.doi.org/10.1155/2019/7609386 |
| spellingShingle | Manpreet K. Parmar Mariam Alikhan Vivien M. Hsu Amanda Borham Echocardiogram: The GPS to GPA’s Heart (Granulomatosis with Polyangiitis) Case Reports in Rheumatology |
| title | Echocardiogram: The GPS to GPA’s Heart (Granulomatosis with Polyangiitis) |
| title_full | Echocardiogram: The GPS to GPA’s Heart (Granulomatosis with Polyangiitis) |
| title_fullStr | Echocardiogram: The GPS to GPA’s Heart (Granulomatosis with Polyangiitis) |
| title_full_unstemmed | Echocardiogram: The GPS to GPA’s Heart (Granulomatosis with Polyangiitis) |
| title_short | Echocardiogram: The GPS to GPA’s Heart (Granulomatosis with Polyangiitis) |
| title_sort | echocardiogram the gps to gpa s heart granulomatosis with polyangiitis |
| url | http://dx.doi.org/10.1155/2019/7609386 |
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