mSphere of Influence: The challenge of screening for essential protein kinases in Trypanosoma cruzi
ABSTRACT Miguel Chiurillo works in the field of protein kinases, studying their role in cell signaling and cell cycle progression in Trypanosoma cruzi. In this mSphere of Influence article, he reflects on how the research articles “Systematic functional analysis of Leishmania protein kinases identif...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2025-02-01
|
| Series: | mSphere |
| Subjects: | |
| Online Access: | https://journals.asm.org/doi/10.1128/msphere.00598-24 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849705846829744128 |
|---|---|
| author | Miguel A. Chiurillo |
| author_facet | Miguel A. Chiurillo |
| author_sort | Miguel A. Chiurillo |
| collection | DOAJ |
| description | ABSTRACT Miguel Chiurillo works in the field of protein kinases, studying their role in cell signaling and cell cycle progression in Trypanosoma cruzi. In this mSphere of Influence article, he reflects on how the research articles “Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival” by Baker et al. and “Screening the Toxoplasma kinome with high throughput tagging identifies a regulator of invasion and egress” by Smith et al. made an impact on his understanding of the complexity of the Trypanosoma cruzi kinome and the challenges to unravel it. |
| format | Article |
| id | doaj-art-7b99ea81709a47de82f40f5c044766b1 |
| institution | DOAJ |
| issn | 2379-5042 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | American Society for Microbiology |
| record_format | Article |
| series | mSphere |
| spelling | doaj-art-7b99ea81709a47de82f40f5c044766b12025-08-20T03:16:22ZengAmerican Society for MicrobiologymSphere2379-50422025-02-0110210.1128/msphere.00598-24mSphere of Influence: The challenge of screening for essential protein kinases in Trypanosoma cruziMiguel A. Chiurillo0Department of Biological Sciences, University of Cincinnati, Cincinnati, Ohio, USAABSTRACT Miguel Chiurillo works in the field of protein kinases, studying their role in cell signaling and cell cycle progression in Trypanosoma cruzi. In this mSphere of Influence article, he reflects on how the research articles “Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival” by Baker et al. and “Screening the Toxoplasma kinome with high throughput tagging identifies a regulator of invasion and egress” by Smith et al. made an impact on his understanding of the complexity of the Trypanosoma cruzi kinome and the challenges to unravel it.https://journals.asm.org/doi/10.1128/msphere.00598-24Trypanosoma cruzikinomabar-seq |
| spellingShingle | Miguel A. Chiurillo mSphere of Influence: The challenge of screening for essential protein kinases in Trypanosoma cruzi mSphere Trypanosoma cruzi kinoma bar-seq |
| title | mSphere of Influence: The challenge of screening for essential protein kinases in Trypanosoma cruzi |
| title_full | mSphere of Influence: The challenge of screening for essential protein kinases in Trypanosoma cruzi |
| title_fullStr | mSphere of Influence: The challenge of screening for essential protein kinases in Trypanosoma cruzi |
| title_full_unstemmed | mSphere of Influence: The challenge of screening for essential protein kinases in Trypanosoma cruzi |
| title_short | mSphere of Influence: The challenge of screening for essential protein kinases in Trypanosoma cruzi |
| title_sort | msphere of influence the challenge of screening for essential protein kinases in trypanosoma cruzi |
| topic | Trypanosoma cruzi kinoma bar-seq |
| url | https://journals.asm.org/doi/10.1128/msphere.00598-24 |
| work_keys_str_mv | AT miguelachiurillo msphereofinfluencethechallengeofscreeningforessentialproteinkinasesintrypanosomacruzi |