PHF20L1: An Epigenetic Regulator in Cancer and Beyond

PHF20L1: An Epigenetic Regulator in Cancer and Beyond

Plant homeodomain (PHD) finger protein 20-like 1 (PHF20L1) is a novel epigenetic “reader” that specifically recognises histone post-translational modifications (PTMs) via its Tudor and PHD finger domains, thereby regulating chromatin remodelling, DNA damage repair, and oncogene transcriptional activ...

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Bibliographic Details
Main Authors: Yishan Wang, Qin Hu, Haixia Zhao, Lulu Zeng, Zhongwei Zhao, Xia Li, Qiaoyou Weng, Yang Yang, Minjiang Chen, Jiansong Ji, Rongfang Qiu
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomolecules
Subjects:
PHF20L1
cancer
epigenetic regulation
histone methylation
targeted therapy
Online Access:https://www.mdpi.com/2218-273X/15/7/1048
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