Associations of serum soluble Fas and Fas ligand (FasL) with outcomes in systemic lupus erythematosus

Associations of serum soluble Fas and Fas ligand (FasL) with outcomes in systemic lupus erythematosus

Objective Fas/Fas ligand (FasL) and B cell-activating factor (BAFF) signalling have pivotal roles in SLE pathogenesis. We investigated the clinical associations of serum concentrations of soluble Fas (sFas) and soluble FasL (sFasL) in SLE and their relationship with BAFF.Methods Serum sFas and sFasL...

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Main Authors: Fabien B Vincent, Alberta Y Hoi, Fabienne Mackay, James Harris, Rangi Kandane-Rathnayake, Eric F Morand, Rachel Koelmeyer
Format: Article
Language:English
Published: BMJ Publishing Group 2020-10-01
Series:Lupus Science and Medicine
Online Access:https://lupus.bmj.com/content/7/1/e000375.full
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