Frontotemporal structure preservation underlies the protective effect of lifetime intellectual cognitive reserve on cognition in the elderly

Abstract Background Cognitive decline with age has heterogeneous, which might be related to the accumulation of protective factors called cognitive reserve, especially intellectual engagement factors over the life course. However, how lifetime intellectual cognitive reserve (LICR) protects cognitive...

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Bibliographic Details
Main Authors: Dandan Wang, Xin Li, Mingxi Dang, Shaokun Zhao, Feng Sang, Zhanjun Zhang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Alzheimer’s Research & Therapy
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Online Access:https://doi.org/10.1186/s13195-024-01613-6
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