Distinct bone metabolic networks identified in Phospho1−/− mice vs. wild type mice using [18F]FDG total-body PET

Distinct bone metabolic networks identified in Phospho1−/− mice vs. wild type mice using [18F]FDG total-body PET

IntroductionTotal-body PET is a recent development in clinical imaging that produces large datasets involving multiple tissues, enabling the use of new analytical methods for multi-organ assessments, such as network analysis—a well-developed method in neuroimaging. The skeletal system provides a goo...

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Bibliographic Details
Main Authors: Abigail F. Hellman, Paul S. Clegg, Colin Farquharson, José Luis Millán, Carlos J. Alcaide-Corral, Karla J. Suchacki, Adriana A. S. Tavares
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Medicine
Subjects:
positron emission tomography
network analysis
systems biology
bone
PHOSPHO1
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1597844/full
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