Gut microbiota diversity is altered in a sex-dependent manner in Shank3B heterozygote mice

Gut microbiota diversity is altered in a sex-dependent manner in Shank3B heterozygote mice

The gut-brain axis is a dynamic interface that has been implicated in the pathogenesis and severity of various neurodevelopmental disorders such as schizophrenia (SZ) and autism spectrum disorders (ASD). Also implicated in ASD and SZ, SHANK3B is a critical gene for postsynaptic protein scaffolding a...

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Bibliographic Details
Main Authors: Finley Turner, Mykle Williams, Sophie Gregoretti, Delano Bielamowicz, Kylie Roach, Lil Gehner, Anjali Kunnatha, Shekinah Phillips, Rosie Hagel, Rebecca Harshman, Erika Vargo, Stacey B. B. Dutton, Jennifer Kovacs, Jennifer Larimore
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Microbiomes
Subjects:
microbiome
schizophrenia
autism spectrum disorder
gut-brain axis
neurodevelopmental disorders
Online Access:https://www.frontiersin.org/articles/10.3389/frmbi.2025.1628819/full
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