The Effectiveness of ICL Implantation in Treating Moderate to High Myopia: Analyzing Changes in Anterior Chamber Parameters
Background: This study aims to assess the efficacy and safety of implantable collamer lens (ICL) implantation in correcting moderate to high myopia, with a particular focus on its impact on anterior segment parameters, including anterior chamber depth (ACD), intraocular pressure (IOP), and endotheli...
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Gujarat Adani Institute of Medical Sciences
2025-07-01
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| Series: | GAIMS Journal of Medical Sciences |
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| Online Access: | https://gjms.gaims.ac.in/index.php/gjms/article/view/318/213 |
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| author | Ankit S Varshney Rumana Z Patel Najwa Mansuri |
| author_facet | Ankit S Varshney Rumana Z Patel Najwa Mansuri |
| author_sort | Ankit S Varshney |
| collection | DOAJ |
| description | Background: This study aims to assess the efficacy and safety of implantable collamer lens (ICL) implantation in correcting moderate to high myopia, with a particular focus on its impact on anterior segment parameters, including anterior chamber depth (ACD), intraocular pressure (IOP), and endothelial cell density.
Material and methods: A prospective, interventional observational study was conducted at a tertiary eye care center from August 2023 to May 2024. Twenty-six patients (44 eyes), aged 18 to 35 years, underwent ICL implantation. Preoperative and one-month postoperative measurements included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), spherical equivalent (SE), IOP, ACD, central corneal thickness (CCT), and endothelial cell counts. Data were analyzed using paired t-tests and ANOVA with IBM SPSS version 25.
Results: The mean preoperative SE improved from −11.49 ± 4.78 D to −0.87 ± 0.40 D postoperatively (p < 0.001). UDVA improved significantly from 0.11 ± 0.035 to 0.87 ± 0.23 (p < 0.001), and CDVA improved from 0.85 ± 0.23 to 1.0 ± 0.18 (p < 0.001). No statistically significant change in IOP was observed (p = 0.2). ACD decreased significantly from 3.32 ± 0.24 mm to 2.59 ± 0.28 mm (p < 0.0001). Endothelial cell count showed a slight but non-significant decrease (p > 0.05).
Conclusion: ICL implantation is a safe and effective option for correcting moderate to high myopia, with significant improvements in visual acuity and acceptable changes in anterior chamber parameters. Ongoing monitoring of anterior segment structures is recommended for long-term safety evaluation. |
| format | Article |
| id | doaj-art-7b7c55cf1b9249ef918c8151b40c8cfe |
| institution | DOAJ |
| issn | 2583-1763 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Gujarat Adani Institute of Medical Sciences |
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| series | GAIMS Journal of Medical Sciences |
| spelling | doaj-art-7b7c55cf1b9249ef918c8151b40c8cfe2025-08-20T03:16:08ZengGujarat Adani Institute of Medical SciencesGAIMS Journal of Medical Sciences2583-17632025-07-01527684https://doi.org/10.5281/zenodo.15803378The Effectiveness of ICL Implantation in Treating Moderate to High Myopia: Analyzing Changes in Anterior Chamber ParametersAnkit S Varshney0Rumana Z Patel1Najwa Mansuri2Department of Optometry, Shree Bharatimaiya College of Optometry & Physiotherapy, Surat, Gujarat, IndiaDepartment of Optometry, Shree Bharatimaiya College of Optometry & Physiotherapy, Surat, Gujarat, IndiaDepartment of Optometry, Shree Bharatimaiya College of Optometry & Physiotherapy, Surat, Gujarat, IndiaBackground: This study aims to assess the efficacy and safety of implantable collamer lens (ICL) implantation in correcting moderate to high myopia, with a particular focus on its impact on anterior segment parameters, including anterior chamber depth (ACD), intraocular pressure (IOP), and endothelial cell density. Material and methods: A prospective, interventional observational study was conducted at a tertiary eye care center from August 2023 to May 2024. Twenty-six patients (44 eyes), aged 18 to 35 years, underwent ICL implantation. Preoperative and one-month postoperative measurements included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), spherical equivalent (SE), IOP, ACD, central corneal thickness (CCT), and endothelial cell counts. Data were analyzed using paired t-tests and ANOVA with IBM SPSS version 25. Results: The mean preoperative SE improved from −11.49 ± 4.78 D to −0.87 ± 0.40 D postoperatively (p < 0.001). UDVA improved significantly from 0.11 ± 0.035 to 0.87 ± 0.23 (p < 0.001), and CDVA improved from 0.85 ± 0.23 to 1.0 ± 0.18 (p < 0.001). No statistically significant change in IOP was observed (p = 0.2). ACD decreased significantly from 3.32 ± 0.24 mm to 2.59 ± 0.28 mm (p < 0.0001). Endothelial cell count showed a slight but non-significant decrease (p > 0.05). Conclusion: ICL implantation is a safe and effective option for correcting moderate to high myopia, with significant improvements in visual acuity and acceptable changes in anterior chamber parameters. Ongoing monitoring of anterior segment structures is recommended for long-term safety evaluation.https://gjms.gaims.ac.in/index.php/gjms/article/view/318/213icl implantationhigh myopiaanterior chamber depthendothelial cell densityrefractive surgeryvisual acuity |
| spellingShingle | Ankit S Varshney Rumana Z Patel Najwa Mansuri The Effectiveness of ICL Implantation in Treating Moderate to High Myopia: Analyzing Changes in Anterior Chamber Parameters GAIMS Journal of Medical Sciences icl implantation high myopia anterior chamber depth endothelial cell density refractive surgery visual acuity |
| title | The Effectiveness of ICL Implantation in Treating Moderate to High Myopia: Analyzing Changes in Anterior Chamber Parameters |
| title_full | The Effectiveness of ICL Implantation in Treating Moderate to High Myopia: Analyzing Changes in Anterior Chamber Parameters |
| title_fullStr | The Effectiveness of ICL Implantation in Treating Moderate to High Myopia: Analyzing Changes in Anterior Chamber Parameters |
| title_full_unstemmed | The Effectiveness of ICL Implantation in Treating Moderate to High Myopia: Analyzing Changes in Anterior Chamber Parameters |
| title_short | The Effectiveness of ICL Implantation in Treating Moderate to High Myopia: Analyzing Changes in Anterior Chamber Parameters |
| title_sort | effectiveness of icl implantation in treating moderate to high myopia analyzing changes in anterior chamber parameters |
| topic | icl implantation high myopia anterior chamber depth endothelial cell density refractive surgery visual acuity |
| url | https://gjms.gaims.ac.in/index.php/gjms/article/view/318/213 |
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