TSLP pretreatment inhibits M1 macrophage polarization and attenuates LPS-induced iNKT cell-dependent acute lung injury

TSLP pretreatment inhibits M1 macrophage polarization and attenuates LPS-induced iNKT cell-dependent acute lung injury

IntroductionSepsis associated acute respiratory distress syndrome (ARDS), is a life-threatening condition characterized by severe pulmonary inflammation. Previous research has suggested that allergic immune diseases are associated with a lower risk of sepsis. Therefore, we hypothesized that certain...

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Bibliographic Details
Main Authors: Ting Zhou, Ziyao Zhang, Yawen Zhan, Meiying Wang, Mi Wu, Xiufang Weng, Younian Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
ARDS
acute lung injury
TSLP
macrophage
iNKT cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1583235/full
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