Continuous Nondestructive Monitoring Method Using the Reconstructed Three-Dimensional Conductivity Images via GREIT for Tissue Engineering
A continuous Nondestructive monitoring method is required to apply proper feedback controls during tissue regeneration. Conductivity is one of valuable information to assess the physiological function and structural formation of regenerated tissues or cultured cells. However, conductivity imaging me...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Journal of Applied Mathematics |
| Online Access: | http://dx.doi.org/10.1155/2014/562176 |
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| _version_ | 1849410590335827968 |
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| author | Sujin Ahn Hun Wi Tong In Oh Alistair Lee McEwan Sung Chan Jun Eung Je Woo |
| author_facet | Sujin Ahn Hun Wi Tong In Oh Alistair Lee McEwan Sung Chan Jun Eung Je Woo |
| author_sort | Sujin Ahn |
| collection | DOAJ |
| description | A continuous Nondestructive monitoring method is required to apply proper feedback controls during tissue regeneration. Conductivity is one of valuable information to assess the physiological function and structural formation of regenerated tissues or cultured cells. However, conductivity imaging methods suffered from inherited ill-posed characteristics in image reconstruction, unknown boundary geometry, uncertainty in electrode position, and systematic artifacts. In order to overcome the limitation of microscopic electrical impedance tomography (micro-EIT), we applied a 3D-specific container with a fixed boundary geometry and electrode configuration to maximize the performance of Graz consensus reconstruction algorithm for EIT (GREIT). The separation of driving and sensing electrodes allows us to simplify the hardware complexity and obtain higher measurement accuracy from a large number of small sensing electrodes. We investigated the applicability of the GREIT to 3D micro-EIT images via numerical simulations and large-scale phantom experiments. We could reconstruct multiple objects regardless of the location. The resolution was 5 mm3 with 30 dB SNR and the position error was less than 2.54 mm. This shows that the new micro-EIT system integrated with GREIT is robust with the intended resolution. With further refinement and scaling down to a microscale container, it may be a continuous nondestructive monitoring tool for tissue engineering applications. |
| format | Article |
| id | doaj-art-7b6e7bfcdcba4b52bfb2ab2d74e6b4ab |
| institution | Kabale University |
| issn | 1110-757X 1687-0042 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Applied Mathematics |
| spelling | doaj-art-7b6e7bfcdcba4b52bfb2ab2d74e6b4ab2025-08-20T03:35:02ZengWileyJournal of Applied Mathematics1110-757X1687-00422014-01-01201410.1155/2014/562176562176Continuous Nondestructive Monitoring Method Using the Reconstructed Three-Dimensional Conductivity Images via GREIT for Tissue EngineeringSujin Ahn0Hun Wi1Tong In Oh2Alistair Lee McEwan3Sung Chan Jun4Eung Je Woo5School of Information & Communications, Gwangju Institute of Science and Technology, Gwangju 500-712, Republic of KoreaImpedance Imaging Research Center and Department of Biomedical Engineering, Kyung Hee University, Yongin 446-701, Republic of KoreaImpedance Imaging Research Center and Department of Biomedical Engineering, Kyung Hee University, Yongin 446-701, Republic of KoreaImpedance Imaging Research Center and Department of Biomedical Engineering, Kyung Hee University, Yongin 446-701, Republic of KoreaSchool of Information & Communications, Gwangju Institute of Science and Technology, Gwangju 500-712, Republic of KoreaImpedance Imaging Research Center and Department of Biomedical Engineering, Kyung Hee University, Yongin 446-701, Republic of KoreaA continuous Nondestructive monitoring method is required to apply proper feedback controls during tissue regeneration. Conductivity is one of valuable information to assess the physiological function and structural formation of regenerated tissues or cultured cells. However, conductivity imaging methods suffered from inherited ill-posed characteristics in image reconstruction, unknown boundary geometry, uncertainty in electrode position, and systematic artifacts. In order to overcome the limitation of microscopic electrical impedance tomography (micro-EIT), we applied a 3D-specific container with a fixed boundary geometry and electrode configuration to maximize the performance of Graz consensus reconstruction algorithm for EIT (GREIT). The separation of driving and sensing electrodes allows us to simplify the hardware complexity and obtain higher measurement accuracy from a large number of small sensing electrodes. We investigated the applicability of the GREIT to 3D micro-EIT images via numerical simulations and large-scale phantom experiments. We could reconstruct multiple objects regardless of the location. The resolution was 5 mm3 with 30 dB SNR and the position error was less than 2.54 mm. This shows that the new micro-EIT system integrated with GREIT is robust with the intended resolution. With further refinement and scaling down to a microscale container, it may be a continuous nondestructive monitoring tool for tissue engineering applications.http://dx.doi.org/10.1155/2014/562176 |
| spellingShingle | Sujin Ahn Hun Wi Tong In Oh Alistair Lee McEwan Sung Chan Jun Eung Je Woo Continuous Nondestructive Monitoring Method Using the Reconstructed Three-Dimensional Conductivity Images via GREIT for Tissue Engineering Journal of Applied Mathematics |
| title | Continuous Nondestructive Monitoring Method Using the Reconstructed Three-Dimensional Conductivity Images via GREIT for Tissue Engineering |
| title_full | Continuous Nondestructive Monitoring Method Using the Reconstructed Three-Dimensional Conductivity Images via GREIT for Tissue Engineering |
| title_fullStr | Continuous Nondestructive Monitoring Method Using the Reconstructed Three-Dimensional Conductivity Images via GREIT for Tissue Engineering |
| title_full_unstemmed | Continuous Nondestructive Monitoring Method Using the Reconstructed Three-Dimensional Conductivity Images via GREIT for Tissue Engineering |
| title_short | Continuous Nondestructive Monitoring Method Using the Reconstructed Three-Dimensional Conductivity Images via GREIT for Tissue Engineering |
| title_sort | continuous nondestructive monitoring method using the reconstructed three dimensional conductivity images via greit for tissue engineering |
| url | http://dx.doi.org/10.1155/2014/562176 |
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