Presumed Retinal Metastasis from Lung Adenocarcinoma: A Case Report and Literature Review
A 63-year-old Caucasian man with metastatic lung adenocarcinoma undergoing chemotherapy and external radiotherapy was referred for routine eye examination. Although he was asymptomatic, ocular examination revealed a relatively well-circumscribed whitish retinal lesion measuring 0.5×0.5×0.5 mm locate...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2021/6615284 |
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| author | Gökçen Özcan Ahmet Kaan Gündüz Ibadulla Mirzayev Ayhan Sağlik |
| author_facet | Gökçen Özcan Ahmet Kaan Gündüz Ibadulla Mirzayev Ayhan Sağlik |
| author_sort | Gökçen Özcan |
| collection | DOAJ |
| description | A 63-year-old Caucasian man with metastatic lung adenocarcinoma undergoing chemotherapy and external radiotherapy was referred for routine eye examination. Although he was asymptomatic, ocular examination revealed a relatively well-circumscribed whitish retinal lesion measuring 0.5×0.5×0.5 mm located along the inferotemporal vascular arcade in the right eye. Optical coherence tomography (OCT) showed a hyperreflective dome-shaped lesion occupying the inner retinal layers with few hyperreflective dots overlying the retina in the posterior vitreous consistent with tumor cells. Fluorescein angiography revealed early hyperfluorescence and late staining without leakage at the lesion site. A diagnosis of presumed retinal metastasis from lung adenocarcinoma was made. At 2 months follow-up after completion of chemotherapy, the retinal lesion was found to have regressed completely leaving minor irregularities in the inner retinal layers on OCT. To date, there have been only 41 cases of carcinoma metastasis to the retina reported in the literature including the current case. Despite its rarity, retinal metastasis should be considered in the differential diagnosis of a white-yellow retinal mass with/without overlying vitreous cells especially in patients with a history of systemic cancer. |
| format | Article |
| id | doaj-art-7b6d06562f174af5a6d0a3017fa56e2b |
| institution | Kabale University |
| issn | 2090-6722 2090-6730 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-7b6d06562f174af5a6d0a3017fa56e2b2025-08-20T03:35:02ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302021-01-01202110.1155/2021/66152846615284Presumed Retinal Metastasis from Lung Adenocarcinoma: A Case Report and Literature ReviewGökçen Özcan0Ahmet Kaan Gündüz1Ibadulla Mirzayev2Ayhan Sağlik3Ankara University Faculty of Medicine, Ophthalmology Department, Ankara, TurkeyAnkara University Faculty of Medicine, Ophthalmology Department, Ankara, TurkeyAnkara University Faculty of Medicine, Ophthalmology Department, Ankara, TurkeyHarran University Faculty of Medicine, Ophthalmology Department, Şanlıurfa, TurkeyA 63-year-old Caucasian man with metastatic lung adenocarcinoma undergoing chemotherapy and external radiotherapy was referred for routine eye examination. Although he was asymptomatic, ocular examination revealed a relatively well-circumscribed whitish retinal lesion measuring 0.5×0.5×0.5 mm located along the inferotemporal vascular arcade in the right eye. Optical coherence tomography (OCT) showed a hyperreflective dome-shaped lesion occupying the inner retinal layers with few hyperreflective dots overlying the retina in the posterior vitreous consistent with tumor cells. Fluorescein angiography revealed early hyperfluorescence and late staining without leakage at the lesion site. A diagnosis of presumed retinal metastasis from lung adenocarcinoma was made. At 2 months follow-up after completion of chemotherapy, the retinal lesion was found to have regressed completely leaving minor irregularities in the inner retinal layers on OCT. To date, there have been only 41 cases of carcinoma metastasis to the retina reported in the literature including the current case. Despite its rarity, retinal metastasis should be considered in the differential diagnosis of a white-yellow retinal mass with/without overlying vitreous cells especially in patients with a history of systemic cancer.http://dx.doi.org/10.1155/2021/6615284 |
| spellingShingle | Gökçen Özcan Ahmet Kaan Gündüz Ibadulla Mirzayev Ayhan Sağlik Presumed Retinal Metastasis from Lung Adenocarcinoma: A Case Report and Literature Review Case Reports in Ophthalmological Medicine |
| title | Presumed Retinal Metastasis from Lung Adenocarcinoma: A Case Report and Literature Review |
| title_full | Presumed Retinal Metastasis from Lung Adenocarcinoma: A Case Report and Literature Review |
| title_fullStr | Presumed Retinal Metastasis from Lung Adenocarcinoma: A Case Report and Literature Review |
| title_full_unstemmed | Presumed Retinal Metastasis from Lung Adenocarcinoma: A Case Report and Literature Review |
| title_short | Presumed Retinal Metastasis from Lung Adenocarcinoma: A Case Report and Literature Review |
| title_sort | presumed retinal metastasis from lung adenocarcinoma a case report and literature review |
| url | http://dx.doi.org/10.1155/2021/6615284 |
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