Strategies for bioresource collection in obstetrics: the experience of the "Genofund" biobank
The article highlights the experience of the "Genofund" biobank of the Ott Research Institute of Obstetrics, Gynecology and Reproductology in bioresource collection in modern obstetrics. To create different types of collections, the following different biobanking strategies were formulated...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2025-01-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/4193 |
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| author | O. V. Pachulia R. A. Illarionov E. S. Vashukova T. B. Postnikova A. R. Maltseva A. K. Popova E. A. Kornyushina O. N. Bespalova A. S. Glotov |
| author_facet | O. V. Pachulia R. A. Illarionov E. S. Vashukova T. B. Postnikova A. R. Maltseva A. K. Popova E. A. Kornyushina O. N. Bespalova A. S. Glotov |
| author_sort | O. V. Pachulia |
| collection | DOAJ |
| description | The article highlights the experience of the "Genofund" biobank of the Ott Research Institute of Obstetrics, Gynecology and Reproductology in bioresource collection in modern obstetrics. To create different types of collections, the following different biobanking strategies were formulated for the first time: cross-sectional and longitudinal (dynamic). Definitions are given for these approaches. The most significant advantages and disadvantages of each of them are noted. Examples of pilot studies conducted on the platform of a bioresource collection created using the complex longitudinal biobanking are given. This approach made it possible to demonstrate, using the example of microRNA analysis, the potential of studying the physiological changes during pregnancy at the present stage, as well as the prospects for finding early predictors of pregnancy complications. |
| format | Article |
| id | doaj-art-7b67ecaa2de044a9b1149b0845cfe7dc |
| institution | DOAJ |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2025-01-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-7b67ecaa2de044a9b1149b0845cfe7dc2025-08-20T03:18:37Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252025-01-01231110.15829/1728-8800-2024-41933114Strategies for bioresource collection in obstetrics: the experience of the "Genofund" biobankO. V. Pachulia0R. A. Illarionov1E. S. Vashukova2T. B. Postnikova3A. R. Maltseva4A. K. Popova5E. A. Kornyushina6O. N. Bespalova7A. S. Glotov8Ott Research Institute of Obstetrics, Gynecology and ReproductologOtt Research Institute of Obstetrics, Gynecology and ReproductologOtt Research Institute of Obstetrics, Gynecology and ReproductologOtt Research Institute of Obstetrics, Gynecology and ReproductologOtt Research Institute of Obstetrics, Gynecology and ReproductologOtt Research Institute of Obstetrics, Gynecology and ReproductologOtt Research Institute of Obstetrics, Gynecology and ReproductologOtt Research Institute of Obstetrics, Gynecology and Reproductolog; Saint Petersburg State UniversityOtt Research Institute of Obstetrics, Gynecology and Reproductolog; Saint Petersburg State UniversityThe article highlights the experience of the "Genofund" biobank of the Ott Research Institute of Obstetrics, Gynecology and Reproductology in bioresource collection in modern obstetrics. To create different types of collections, the following different biobanking strategies were formulated for the first time: cross-sectional and longitudinal (dynamic). Definitions are given for these approaches. The most significant advantages and disadvantages of each of them are noted. Examples of pilot studies conducted on the platform of a bioresource collection created using the complex longitudinal biobanking are given. This approach made it possible to demonstrate, using the example of microRNA analysis, the potential of studying the physiological changes during pregnancy at the present stage, as well as the prospects for finding early predictors of pregnancy complications.https://cardiovascular.elpub.ru/jour/article/view/4193bioresource collectionslongitudinal bankingcross-sectional bankingpregnancypregnancy physiologypregnancy complications |
| spellingShingle | O. V. Pachulia R. A. Illarionov E. S. Vashukova T. B. Postnikova A. R. Maltseva A. K. Popova E. A. Kornyushina O. N. Bespalova A. S. Glotov Strategies for bioresource collection in obstetrics: the experience of the "Genofund" biobank Кардиоваскулярная терапия и профилактика bioresource collections longitudinal banking cross-sectional banking pregnancy pregnancy physiology pregnancy complications |
| title | Strategies for bioresource collection in obstetrics: the experience of the "Genofund" biobank |
| title_full | Strategies for bioresource collection in obstetrics: the experience of the "Genofund" biobank |
| title_fullStr | Strategies for bioresource collection in obstetrics: the experience of the "Genofund" biobank |
| title_full_unstemmed | Strategies for bioresource collection in obstetrics: the experience of the "Genofund" biobank |
| title_short | Strategies for bioresource collection in obstetrics: the experience of the "Genofund" biobank |
| title_sort | strategies for bioresource collection in obstetrics the experience of the genofund biobank |
| topic | bioresource collections longitudinal banking cross-sectional banking pregnancy pregnancy physiology pregnancy complications |
| url | https://cardiovascular.elpub.ru/jour/article/view/4193 |
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