Subclassification of Follicular Neoplasms Recommended by the Japan Thyroid Association Reporting System of Thyroid Cytology
Background. The Japan Thyroid Association recently published guidelines for clinical practice for the management of thyroid nodules, which include a diagnostic system for reporting thyroid fine needle aspiration cytology. It is characterized by the subclassification of follicular neoplasms, which is...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2015/938305 |
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| author | Kennichi Kakudo Kaori Kameyama Mitsuyoshi Hirokawa Ryohei Katoh Hirotoshi Nakamura |
| author_facet | Kennichi Kakudo Kaori Kameyama Mitsuyoshi Hirokawa Ryohei Katoh Hirotoshi Nakamura |
| author_sort | Kennichi Kakudo |
| collection | DOAJ |
| description | Background. The Japan Thyroid Association recently published guidelines for clinical practice for the management of thyroid nodules, which include a diagnostic system for reporting thyroid fine needle aspiration cytology. It is characterized by the subclassification of follicular neoplasms, which is different from other internationally accepted reporting systems. Materials and Methods. This study examined observer variability in the subclassification of follicular neoplasms among 4 reviewers using Papanicolaou-stained smear samples from 20 surgically treated patients with indeterminate cytology. Results. The favor malignant subcategory had high predictive value of malignancy (risk of malignancy: 60–75%) and good agreement among the 4 reviewers (κ=0.7714). Conclusion. These results clearly confirmed that the risk stratification of follicular neoplasms, which was adapted from cytology practice of high-volume thyroid centers in Japan, can provide clinically helpful information to estimate the risk of malignancy and to triage patients for surgery. |
| format | Article |
| id | doaj-art-7b57855cd17e4e3aa9f1df4780cd6e12 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-7b57855cd17e4e3aa9f1df4780cd6e122025-08-20T03:35:03ZengWileyInternational Journal of Endocrinology1687-83371687-83452015-01-01201510.1155/2015/938305938305Subclassification of Follicular Neoplasms Recommended by the Japan Thyroid Association Reporting System of Thyroid CytologyKennichi Kakudo0Kaori Kameyama1Mitsuyoshi Hirokawa2Ryohei Katoh3Hirotoshi Nakamura4Department of Pathology, Nara Hospital, Kinki University Faculty of Medicine, Otoda-cho 1248-1, Ikoma, Nara 630-0293, JapanDivision of Diagnostic Pathology, Keio University School of Medicine, Tokyo 160-8582, JapanDepartment of Pathology, Kuma Hospital, Kobe 650-0011, JapanDepartment of Human Pathology, Yamanashi University School of Medicine, Yamanashi 409-3898, JapanDepartment of Internal Medicine, Kuma Hospital, Kobe 650-0011, JapanBackground. The Japan Thyroid Association recently published guidelines for clinical practice for the management of thyroid nodules, which include a diagnostic system for reporting thyroid fine needle aspiration cytology. It is characterized by the subclassification of follicular neoplasms, which is different from other internationally accepted reporting systems. Materials and Methods. This study examined observer variability in the subclassification of follicular neoplasms among 4 reviewers using Papanicolaou-stained smear samples from 20 surgically treated patients with indeterminate cytology. Results. The favor malignant subcategory had high predictive value of malignancy (risk of malignancy: 60–75%) and good agreement among the 4 reviewers (κ=0.7714). Conclusion. These results clearly confirmed that the risk stratification of follicular neoplasms, which was adapted from cytology practice of high-volume thyroid centers in Japan, can provide clinically helpful information to estimate the risk of malignancy and to triage patients for surgery.http://dx.doi.org/10.1155/2015/938305 |
| spellingShingle | Kennichi Kakudo Kaori Kameyama Mitsuyoshi Hirokawa Ryohei Katoh Hirotoshi Nakamura Subclassification of Follicular Neoplasms Recommended by the Japan Thyroid Association Reporting System of Thyroid Cytology International Journal of Endocrinology |
| title | Subclassification of Follicular Neoplasms Recommended by the Japan Thyroid Association Reporting System of Thyroid Cytology |
| title_full | Subclassification of Follicular Neoplasms Recommended by the Japan Thyroid Association Reporting System of Thyroid Cytology |
| title_fullStr | Subclassification of Follicular Neoplasms Recommended by the Japan Thyroid Association Reporting System of Thyroid Cytology |
| title_full_unstemmed | Subclassification of Follicular Neoplasms Recommended by the Japan Thyroid Association Reporting System of Thyroid Cytology |
| title_short | Subclassification of Follicular Neoplasms Recommended by the Japan Thyroid Association Reporting System of Thyroid Cytology |
| title_sort | subclassification of follicular neoplasms recommended by the japan thyroid association reporting system of thyroid cytology |
| url | http://dx.doi.org/10.1155/2015/938305 |
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