Estimating the effect of tissue- and blood-derived cell reference matrices on deconvolving bulk transcriptomic datasets
Cell deconvolution is a widely used method to characterize the composition of the mixed cell population in bulk transcriptomic datasets. While tissue- and blood-derived cell reference matrices (CRMs) are commonly used, their impact on deconvolution accuracy has yet to be systematically evaluated. In...
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| Main Authors: | Siqi Sun, Shweta Yadav, Mulini Pingili, Dan Chang, Jing Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
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| Series: | Computational and Structural Biotechnology Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037025003216 |
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