Estrogen Receptor Beta Agonist Influences Presynaptic NMDA Receptor Distribution in the Paraventricular Hypothalamic Nucleus Following Hypertension in a Mouse Model of Perimenopause

Estrogen Receptor Beta Agonist Influences Presynaptic NMDA Receptor Distribution in the Paraventricular Hypothalamic Nucleus Following Hypertension in a Mouse Model of Perimenopause

Women become susceptible to hypertension as they transition to menopause (i.e., perimenopause); however, the underlying mechanisms are unclear. Animal studies using an accelerated ovarian failure (AOF) model of peri-menopause (peri-AOF) demonstrate that peri-AOF hypertension is associated with incre...

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Bibliographic Details
Main Authors: Garrett Sommer, Claudia Rodríguez López, Adi Hirschkorn, Gianna Calimano, Jose Marques-Lopes, Teresa A. Milner, Michael J. Glass
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Biology
Subjects:
estrogens
estrogen receptor beta
menopause
neural plasticity
Online Access:https://www.mdpi.com/2079-7737/13/10/819
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