Loss of Ambulation Due to Calcific Myonecrosis: A Rare but Reversible Complication of Wilson’s Disease
We report two cases of established Wilson’s disease (WD) presenting with calcific myonecrosis of the pelvic girdle in association with pelvic fractures. Despite initial improvement with chelation, subacute worsening of ambulation in both led to a consideration of neurologic deterioration on chelatio...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Annals of Indian Academy of Neurology |
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| Online Access: | https://journals.lww.com/10.4103/aian.aian_419_24 |
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| author | Abhishek Vaingankar Divyani Garg Ayush Agarwal Divya M Radhakrishnan Awadh Kishor Pandit Madhavi Tripathi Achal K Srivastava |
| author_facet | Abhishek Vaingankar Divyani Garg Ayush Agarwal Divya M Radhakrishnan Awadh Kishor Pandit Madhavi Tripathi Achal K Srivastava |
| author_sort | Abhishek Vaingankar |
| collection | DOAJ |
| description | We report two cases of established Wilson’s disease (WD) presenting with calcific myonecrosis of the pelvic girdle in association with pelvic fractures. Despite initial improvement with chelation, subacute worsening of ambulation in both led to a consideration of neurologic deterioration on chelation therapy. However, evaluation revealed calcific myonecrosis of the hip joint and adjacent muscles as the cause. Both patients improved with intensive rehabilitation. A review of literature indicates that although osseomuscular complications are reported in WD, calcific myonecrosis is a hitherto unknown entity which, if recognized early, may be reversed, preventing disability and unnecessary change in chelation regimens. |
| format | Article |
| id | doaj-art-7b2bb98b8c5247be9c4b7170973c6b16 |
| institution | Kabale University |
| issn | 0972-2327 1998-3549 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Annals of Indian Academy of Neurology |
| spelling | doaj-art-7b2bb98b8c5247be9c4b7170973c6b162025-01-06T14:22:14ZengWolters Kluwer Medknow PublicationsAnnals of Indian Academy of Neurology0972-23271998-35492024-12-0127672472610.4103/aian.aian_419_24Loss of Ambulation Due to Calcific Myonecrosis: A Rare but Reversible Complication of Wilson’s DiseaseAbhishek VaingankarDivyani GargAyush AgarwalDivya M RadhakrishnanAwadh Kishor PanditMadhavi TripathiAchal K SrivastavaWe report two cases of established Wilson’s disease (WD) presenting with calcific myonecrosis of the pelvic girdle in association with pelvic fractures. Despite initial improvement with chelation, subacute worsening of ambulation in both led to a consideration of neurologic deterioration on chelation therapy. However, evaluation revealed calcific myonecrosis of the hip joint and adjacent muscles as the cause. Both patients improved with intensive rehabilitation. A review of literature indicates that although osseomuscular complications are reported in WD, calcific myonecrosis is a hitherto unknown entity which, if recognized early, may be reversed, preventing disability and unnecessary change in chelation regimens.https://journals.lww.com/10.4103/aian.aian_419_24copperfractureosseomuscularpelvis |
| spellingShingle | Abhishek Vaingankar Divyani Garg Ayush Agarwal Divya M Radhakrishnan Awadh Kishor Pandit Madhavi Tripathi Achal K Srivastava Loss of Ambulation Due to Calcific Myonecrosis: A Rare but Reversible Complication of Wilson’s Disease Annals of Indian Academy of Neurology copper fracture osseomuscular pelvis |
| title | Loss of Ambulation Due to Calcific Myonecrosis: A Rare but Reversible Complication of Wilson’s Disease |
| title_full | Loss of Ambulation Due to Calcific Myonecrosis: A Rare but Reversible Complication of Wilson’s Disease |
| title_fullStr | Loss of Ambulation Due to Calcific Myonecrosis: A Rare but Reversible Complication of Wilson’s Disease |
| title_full_unstemmed | Loss of Ambulation Due to Calcific Myonecrosis: A Rare but Reversible Complication of Wilson’s Disease |
| title_short | Loss of Ambulation Due to Calcific Myonecrosis: A Rare but Reversible Complication of Wilson’s Disease |
| title_sort | loss of ambulation due to calcific myonecrosis a rare but reversible complication of wilson s disease |
| topic | copper fracture osseomuscular pelvis |
| url | https://journals.lww.com/10.4103/aian.aian_419_24 |
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