Impact of exercise-based cardiac rehabilitation on cardiopulmonary function and prognosis in ST elevation myocardial infarction after PCI patients in extremely cold regions

Abstract Purpose To evaluate the impact of exercise-based cardiac rehabilitation (CR) on the cardiopulmonary function and prognosis in post-percutaneous coronary intervention (PCI) patients with ST elevation myocardial infarction (STEMI) in extremely cold regions of China. Methods This retrospective...

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Main Authors: Shenglong Hou, Li Liu, Jing Yao, Qi Zhao, Wei Feng, Qingqing Liu, Mou Zou, Ruoxi Zhang, Hongtao Yin, Huimin Xian
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Cardiovascular Disorders
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Online Access:https://doi.org/10.1186/s12872-025-04521-1
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author Shenglong Hou
Li Liu
Jing Yao
Qi Zhao
Wei Feng
Qingqing Liu
Mou Zou
Ruoxi Zhang
Hongtao Yin
Huimin Xian
author_facet Shenglong Hou
Li Liu
Jing Yao
Qi Zhao
Wei Feng
Qingqing Liu
Mou Zou
Ruoxi Zhang
Hongtao Yin
Huimin Xian
author_sort Shenglong Hou
collection DOAJ
description Abstract Purpose To evaluate the impact of exercise-based cardiac rehabilitation (CR) on the cardiopulmonary function and prognosis in post-percutaneous coronary intervention (PCI) patients with ST elevation myocardial infarction (STEMI) in extremely cold regions of China. Methods This retrospective study included 2,162 patients diagnosed with STEMI who were treated at five medical centers in extremely cold regions of China, between January 2020 and December 2023. All included patients underwent emergency coronary angiography and PCI. Based on whether they received exercise-based CR, patients were divided into a CR group and a non-CR group. To adjust for variations in initial risk factors and baseline characteristics between patients who underwent CR or not, we employed the propensity score matching. Each patient was matched in a 1:1 ratio with replacement. Patients who either participated in CR or did not, but could not be adequately matched, were excluded from the study population. Patient information between the two groups was systematically compared in hospital and at follow-up. Results The rate of heart failure, re-hospitalization, and ventricular arrhythmia in CR group was significantly lower than that in non-CR group. The left ventricular ejection fraction (LVEF) measured by echocardiography in CR group were significantly higher than those in non-CR group. The cardiopulmonary test indicators for patients in CR group showed significant improvement over one year, including Power, HR, VCO₂, VO₂, VE, VD/VT, PetCO₂, CHO, CO, and SV, all with statistical significance. Multivariate COX regression analysis showed that CR was independently associated with heart failure in follow up. Conclusion Exercise-based CR effectively improves the recovery of cardiac function and prognosis in post-PCI patients with STEMI in extremely cold regions of China. Graphical Abstract
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spelling doaj-art-7b2aecedc5ab426db0372b5c6a973ee72025-02-09T12:11:13ZengBMCBMC Cardiovascular Disorders1471-22612025-02-0125111110.1186/s12872-025-04521-1Impact of exercise-based cardiac rehabilitation on cardiopulmonary function and prognosis in ST elevation myocardial infarction after PCI patients in extremely cold regionsShenglong Hou0Li Liu1Jing Yao2Qi Zhao3Wei Feng4Qingqing Liu5Mou Zou6Ruoxi Zhang7Hongtao Yin8Huimin Xian9Department of Cardiology, Heilongjiang Provincial People’s HospitalDepartment of Cardiology, First Hospital of Harbin Medical UniversityDepartment of Cardiology, Hegang People’s HospitalDepartment of Cardiology, First Hospital of Harbin Medical UniversityDepartment of Cardiology, First Hospital of Harbin Medical UniversityDepartment of Cardiology, First Hospital of Harbin Medical UniversityDepartment of Cardiology, First Hospital of China Medical UniversityDepartment of Cardiology, Harbin Yinghua HospitalDepartment of Cardiology, Harbin Medical University Cancer HospitalDepartment of Cardiology, Second Hospital of Harbin Medical UniversityAbstract Purpose To evaluate the impact of exercise-based cardiac rehabilitation (CR) on the cardiopulmonary function and prognosis in post-percutaneous coronary intervention (PCI) patients with ST elevation myocardial infarction (STEMI) in extremely cold regions of China. Methods This retrospective study included 2,162 patients diagnosed with STEMI who were treated at five medical centers in extremely cold regions of China, between January 2020 and December 2023. All included patients underwent emergency coronary angiography and PCI. Based on whether they received exercise-based CR, patients were divided into a CR group and a non-CR group. To adjust for variations in initial risk factors and baseline characteristics between patients who underwent CR or not, we employed the propensity score matching. Each patient was matched in a 1:1 ratio with replacement. Patients who either participated in CR or did not, but could not be adequately matched, were excluded from the study population. Patient information between the two groups was systematically compared in hospital and at follow-up. Results The rate of heart failure, re-hospitalization, and ventricular arrhythmia in CR group was significantly lower than that in non-CR group. The left ventricular ejection fraction (LVEF) measured by echocardiography in CR group were significantly higher than those in non-CR group. The cardiopulmonary test indicators for patients in CR group showed significant improvement over one year, including Power, HR, VCO₂, VO₂, VE, VD/VT, PetCO₂, CHO, CO, and SV, all with statistical significance. Multivariate COX regression analysis showed that CR was independently associated with heart failure in follow up. Conclusion Exercise-based CR effectively improves the recovery of cardiac function and prognosis in post-PCI patients with STEMI in extremely cold regions of China. Graphical Abstracthttps://doi.org/10.1186/s12872-025-04521-1Exercise-based cardiac rehabilitationMyocardial infarctionCold regionsPost-PCICardiac functionPrognosis
spellingShingle Shenglong Hou
Li Liu
Jing Yao
Qi Zhao
Wei Feng
Qingqing Liu
Mou Zou
Ruoxi Zhang
Hongtao Yin
Huimin Xian
Impact of exercise-based cardiac rehabilitation on cardiopulmonary function and prognosis in ST elevation myocardial infarction after PCI patients in extremely cold regions
BMC Cardiovascular Disorders
Exercise-based cardiac rehabilitation
Myocardial infarction
Cold regions
Post-PCI
Cardiac function
Prognosis
title Impact of exercise-based cardiac rehabilitation on cardiopulmonary function and prognosis in ST elevation myocardial infarction after PCI patients in extremely cold regions
title_full Impact of exercise-based cardiac rehabilitation on cardiopulmonary function and prognosis in ST elevation myocardial infarction after PCI patients in extremely cold regions
title_fullStr Impact of exercise-based cardiac rehabilitation on cardiopulmonary function and prognosis in ST elevation myocardial infarction after PCI patients in extremely cold regions
title_full_unstemmed Impact of exercise-based cardiac rehabilitation on cardiopulmonary function and prognosis in ST elevation myocardial infarction after PCI patients in extremely cold regions
title_short Impact of exercise-based cardiac rehabilitation on cardiopulmonary function and prognosis in ST elevation myocardial infarction after PCI patients in extremely cold regions
title_sort impact of exercise based cardiac rehabilitation on cardiopulmonary function and prognosis in st elevation myocardial infarction after pci patients in extremely cold regions
topic Exercise-based cardiac rehabilitation
Myocardial infarction
Cold regions
Post-PCI
Cardiac function
Prognosis
url https://doi.org/10.1186/s12872-025-04521-1
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