WNT-Pathway Activation in IBD-Associated Colorectal Carcinogenesis: Potential Biomarkers for Colonic Surveillance
Objectives: The Wnt-pathway dominates the sporadic carcinogenesis whereas p53 plays a pivotal role in the colitis-associated counterpart. The expression of Wnt-signaling proteins and p53 during colitis-associated carcinogenesis was determined.
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2010-01-01
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| Series: | Cellular Oncology |
| Online Access: | http://dx.doi.org/10.3233/CLO-2009-0503 |
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| _version_ | 1832568222031806464 |
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| author | Marian M. H. Claessen Marguerite E. I. Schipper Bas Oldenburg Peter D. Siersema G. Johan A. Offerhaus Frank P. Vleggaar |
| author_facet | Marian M. H. Claessen Marguerite E. I. Schipper Bas Oldenburg Peter D. Siersema G. Johan A. Offerhaus Frank P. Vleggaar |
| author_sort | Marian M. H. Claessen |
| collection | DOAJ |
| description | Objectives: The Wnt-pathway dominates the sporadic carcinogenesis whereas p53 plays a pivotal role in the colitis-associated counterpart. The expression of Wnt-signaling proteins and p53 during colitis-associated carcinogenesis was determined. |
| format | Article |
| id | doaj-art-7b22a73ba65746b0940c0b649fbcdcaf |
| institution | Kabale University |
| issn | 1570-5870 1875-8606 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cellular Oncology |
| spelling | doaj-art-7b22a73ba65746b0940c0b649fbcdcaf2025-02-03T00:59:34ZengWileyCellular Oncology1570-58701875-86062010-01-0132430331010.3233/CLO-2009-0503WNT-Pathway Activation in IBD-Associated Colorectal Carcinogenesis: Potential Biomarkers for Colonic SurveillanceMarian M. H. Claessen0Marguerite E. I. Schipper1Bas Oldenburg2Peter D. Siersema3G. Johan A. Offerhaus4Frank P. Vleggaar5Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The NetherlandsDepartment of Pathology, University Medical Center Utrecht, Utrecht, The NetherlandsDepartment of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The NetherlandsDepartment of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The NetherlandsDepartment of Pathology, University Medical Center Utrecht, Utrecht, The NetherlandsDepartment of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The NetherlandsObjectives: The Wnt-pathway dominates the sporadic carcinogenesis whereas p53 plays a pivotal role in the colitis-associated counterpart. The expression of Wnt-signaling proteins and p53 during colitis-associated carcinogenesis was determined.http://dx.doi.org/10.3233/CLO-2009-0503 |
| spellingShingle | Marian M. H. Claessen Marguerite E. I. Schipper Bas Oldenburg Peter D. Siersema G. Johan A. Offerhaus Frank P. Vleggaar WNT-Pathway Activation in IBD-Associated Colorectal Carcinogenesis: Potential Biomarkers for Colonic Surveillance Cellular Oncology |
| title | WNT-Pathway Activation in IBD-Associated Colorectal Carcinogenesis: Potential Biomarkers for Colonic Surveillance |
| title_full | WNT-Pathway Activation in IBD-Associated Colorectal Carcinogenesis: Potential Biomarkers for Colonic Surveillance |
| title_fullStr | WNT-Pathway Activation in IBD-Associated Colorectal Carcinogenesis: Potential Biomarkers for Colonic Surveillance |
| title_full_unstemmed | WNT-Pathway Activation in IBD-Associated Colorectal Carcinogenesis: Potential Biomarkers for Colonic Surveillance |
| title_short | WNT-Pathway Activation in IBD-Associated Colorectal Carcinogenesis: Potential Biomarkers for Colonic Surveillance |
| title_sort | wnt pathway activation in ibd associated colorectal carcinogenesis potential biomarkers for colonic surveillance |
| url | http://dx.doi.org/10.3233/CLO-2009-0503 |
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