Epidermal Growth Factor Receptor Mutated Lung Cancer Presenting as Synchronous with a Recurrent Nonhuman Papillomavirus-Related Head-and-Neck Squamous Cell Carcinoma
A patient with nonhuman papillomavirus (HPV)-related head-and-neck cancers is at an increased risk of developing second primary malignancies. We present a case of non-HPV-related squamous cell carcinoma (SCC) of the left lower alveolus who presented with locoregional recurrence in the left upper lip...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer – Medknow Publications
2021-07-01
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| Series: | Journal of Integrated Health Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jihs.jihs_17_21 |
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| Summary: | A patient with nonhuman papillomavirus (HPV)-related head-and-neck cancers is at an increased risk of developing second primary malignancies. We present a case of non-HPV-related squamous cell carcinoma (SCC) of the left lower alveolus who presented with locoregional recurrence in the left upper lip 3 years after initial treatment with chemoradiotherapy along with a synchronous Epidermal growth factor receptor(EGFR)mutated lung adenocarcinoma. Comprehensive genomic profiling will guide diagnosis and therapy in these cases. Registry of synchronous tumors would help design protocols for better management. |
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| ISSN: | 2347-6486 2347-6494 |