Metallothionein 3 attenuated the apoptosis of neurons in the CA1 region of the hippocampus in the senescence-accelerated mouse/PRONE8 (SAMP8)

OBJECTIVE: Metallothionein 3 (MT-3) has been shown to protect against apoptotic neuronal death in the brains of patients with Alzheimer's disease. Zinc is a potent inhibitor of caspase-3 and its deficiency was found to promote apoptosis. Here, we measured the zinc and copper content in the brai...

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Bibliographic Details
Main Authors: Feiyu Ma, Hu Wang, Bin Chen, Feng Wang, Haixiong Xu
Format: Article
Language:English
Published: Thieme Revinter Publicações 2011-02-01
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000100020&lng=en&tlng=en
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