Machine learning-based phenotypic imaging to characterise the targetable biology of Plasmodium falciparum male gametocytes for the development of transmission-blocking antimalarials.
Preventing parasite transmission from humans to mosquitoes is recognised to be critical for achieving elimination and eradication of malaria. Consequently developing new antimalarial drugs with transmission-blocking properties is a priority. Large screening campaigns have identified many new transmi...
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| Main Authors: | Oleksiy Tsebriy, Andrii Khomiak, Celia Miguel-Blanco, Penny C Sparkes, Maurizio Gioli, Marco Santelli, Edgar Whitley, Francisco-Javier Gamo, Michael J Delves |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2023-10-01
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| Series: | PLoS Pathogens |
| Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011711&type=printable |
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