Buccal Fat Pad as a Potential Source of Stem Cells for Bone Regeneration: A Literature Review
Adipose tissues hold great promise in bone tissue engineering since they are available in large quantities as a waste material. The buccal fat pad (BFP) is a specialized adipose tissue that is easy to harvest and contains a rich blood supply, and its harvesting causes low complications for patients....
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Stem Cells International |
| Online Access: | http://dx.doi.org/10.1155/2017/8354640 |
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| _version_ | 1850220490424057856 |
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| author | Nasim Salehi-Nik Maryam Rezai Rad Lida Kheiri Pantea Nazeman Nasser Nadjmi Arash Khojasteh |
| author_facet | Nasim Salehi-Nik Maryam Rezai Rad Lida Kheiri Pantea Nazeman Nasser Nadjmi Arash Khojasteh |
| author_sort | Nasim Salehi-Nik |
| collection | DOAJ |
| description | Adipose tissues hold great promise in bone tissue engineering since they are available in large quantities as a waste material. The buccal fat pad (BFP) is a specialized adipose tissue that is easy to harvest and contains a rich blood supply, and its harvesting causes low complications for patients. This review focuses on the characteristics and osteogenic capability of stem cells derived from BFP as a valuable cell source for bone tissue engineering. An electronic search was performed on all in vitro and in vivo studies that used stem cells from BFP for the purpose of bone tissue engineering from 2010 until 2016. This review was organized according to the PRISMA statement. Adipose-derived stem cells derived from BFP (BFPSCs) were compared with adipose tissues from other parts of the body (AdSCs). Moreover, the osteogenic capability of dedifferentiated fat cells (DFAT) derived from BFP (BFP-DFAT) has been reported in comparison with BFPSCs. BFP is an easily accessible source of stem cells that can be obtained via the oral cavity without injury to the external body surface. Comparing BFPSCs with AdSCs indicated similar cell yield, morphology, and multilineage differentiation. However, BFPSCs proliferate faster and are more prone to producing colonies than AdSCs. |
| format | Article |
| id | doaj-art-7afe9a27fd4d4a5ea46fbc8c732488a8 |
| institution | OA Journals |
| issn | 1687-966X 1687-9678 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stem Cells International |
| spelling | doaj-art-7afe9a27fd4d4a5ea46fbc8c732488a82025-08-20T02:07:02ZengWileyStem Cells International1687-966X1687-96782017-01-01201710.1155/2017/83546408354640Buccal Fat Pad as a Potential Source of Stem Cells for Bone Regeneration: A Literature ReviewNasim Salehi-Nik0Maryam Rezai Rad1Lida Kheiri2Pantea Nazeman3Nasser Nadjmi4Arash Khojasteh5Department of Tissue Engineering, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranDental Research Center, Research Institute of Dental Sciences, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, IranSchool of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, IranDental Research Center, Research Institute of Dental Sciences, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, IranUniversity of Antwerp, The Team for Cleft and Craniofacial Anomalies, Oral and Maxillofacial Surgery, University of Antwerp, Antwerp, BelgiumDepartment of Tissue Engineering, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranAdipose tissues hold great promise in bone tissue engineering since they are available in large quantities as a waste material. The buccal fat pad (BFP) is a specialized adipose tissue that is easy to harvest and contains a rich blood supply, and its harvesting causes low complications for patients. This review focuses on the characteristics and osteogenic capability of stem cells derived from BFP as a valuable cell source for bone tissue engineering. An electronic search was performed on all in vitro and in vivo studies that used stem cells from BFP for the purpose of bone tissue engineering from 2010 until 2016. This review was organized according to the PRISMA statement. Adipose-derived stem cells derived from BFP (BFPSCs) were compared with adipose tissues from other parts of the body (AdSCs). Moreover, the osteogenic capability of dedifferentiated fat cells (DFAT) derived from BFP (BFP-DFAT) has been reported in comparison with BFPSCs. BFP is an easily accessible source of stem cells that can be obtained via the oral cavity without injury to the external body surface. Comparing BFPSCs with AdSCs indicated similar cell yield, morphology, and multilineage differentiation. However, BFPSCs proliferate faster and are more prone to producing colonies than AdSCs.http://dx.doi.org/10.1155/2017/8354640 |
| spellingShingle | Nasim Salehi-Nik Maryam Rezai Rad Lida Kheiri Pantea Nazeman Nasser Nadjmi Arash Khojasteh Buccal Fat Pad as a Potential Source of Stem Cells for Bone Regeneration: A Literature Review Stem Cells International |
| title | Buccal Fat Pad as a Potential Source of Stem Cells for Bone Regeneration: A Literature Review |
| title_full | Buccal Fat Pad as a Potential Source of Stem Cells for Bone Regeneration: A Literature Review |
| title_fullStr | Buccal Fat Pad as a Potential Source of Stem Cells for Bone Regeneration: A Literature Review |
| title_full_unstemmed | Buccal Fat Pad as a Potential Source of Stem Cells for Bone Regeneration: A Literature Review |
| title_short | Buccal Fat Pad as a Potential Source of Stem Cells for Bone Regeneration: A Literature Review |
| title_sort | buccal fat pad as a potential source of stem cells for bone regeneration a literature review |
| url | http://dx.doi.org/10.1155/2017/8354640 |
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