p38 mediated ACSL4 phosphorylation drives stress-induced esophageal squamous cell carcinoma growth through Src myristoylation

p38 mediated ACSL4 phosphorylation drives stress-induced esophageal squamous cell carcinoma growth through Src myristoylation

Abstract The comprehension of intricate molecular mechanisms underlying how external stimuli promote malignancy is conducive to cancer early prevention. Esophageal squamous cell carcinoma (ESCC) is considered as an external stimuli (hot foods, tobacco, chemo-compounds) induced cancer, characterized...

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Main Authors: Qiang Yuan, Yunshu Shi, Junyong Wang, Yifei Xie, Xiaoyu Li, Jimin Zhao, Yanan Jiang, Yan Qiao, Yaping Guo, Chengjuan Zhang, Jing Lu, Tongjin Zhao, Ziming Dong, Peng Li, Zigang Dong, Kangdong Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58342-z
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