EPILEPSY SURGERY IN PATIENTS WITH TUBEROUS SCLEROSIS
With a few exceptions patients with tuberous sclerosis (TS) suffering from drug-resistant epilepsies have potentially epileptogenic lesionswithin both hemispheres. Until one decade ago in general such a constellation was an xclusion criteria for considerations with respect to epilepsy surgery. Howev...
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ABV-press
2015-04-01
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| Series: | Русский журнал детской неврологии |
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| Online Access: | https://rjdn.abvpress.ru/jour/article/view/46 |
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| author | Hans Holthausen Tom Pieper Hans Eitel Manfred Kudernatsch |
| author_facet | Hans Holthausen Tom Pieper Hans Eitel Manfred Kudernatsch |
| author_sort | Hans Holthausen |
| collection | DOAJ |
| description | With a few exceptions patients with tuberous sclerosis (TS) suffering from drug-resistant epilepsies have potentially epileptogenic lesionswithin both hemispheres. Until one decade ago in general such a constellation was an xclusion criteria for considerations with respect to epilepsy surgery. However experience has shown that it is not so rare to find patients in whom over the ears seizures are generated from just one single focus and that these patients can be good candidates for epilepsy surgery. Almost revolutionary was the further evelopment: multi-step procedures in patients with bilateral epileptogenic lesions – with promising results in terms of postoperative seizure outcome. Also, with increasing experience, it becomes more and more possible to differentiate already non-invasively which lesions could be epileptogenic and which are rather not the source of the seizures. The most important achievement of epilepsy surgery in TS however is that in selected cases early surgical intervention is able to prevent severe mental retardations, which are often the main burden for families who have members with this peculiar disease. |
| format | Article |
| id | doaj-art-7ad98ff4292c40e084046596497e8bea |
| institution | Kabale University |
| issn | 2073-8803 2412-9178 |
| language | Russian |
| publishDate | 2015-04-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Русский журнал детской неврологии |
| spelling | doaj-art-7ad98ff4292c40e084046596497e8bea2025-08-20T03:44:13ZrusABV-pressРусский журнал детской неврологии2073-88032412-91782015-04-01101404610.17650/2073-8803-2015-1-40-4640EPILEPSY SURGERY IN PATIENTS WITH TUBEROUS SCLEROSISHans Holthausen0Tom Pieper1Hans Eitel2Manfred Kudernatsch3Neuropediatric Clinic and Clinic for Neurorehabiltation, Epilepsy Center for Children and Adolescents; Schoen-Klinik Vogtareuth; 20 Krankenhausstrasse, D-83569, Vogtareuth, DeutschlandNeuropediatric Clinic and Clinic for Neurorehabiltation, Epilepsy Center for Children and Adolescents; Schoen-Klinik Vogtareuth; 20 Krankenhausstrasse, D-83569, Vogtareuth, DeutschlandNeuropediatric Clinic and Clinic for Neurorehabiltation, Epilepsy Center for Children and Adolescents; Schoen-Klinik Vogtareuth; 20 Krankenhausstrasse, D-83569, Vogtareuth, DeutschlandNeurosurgery Clinic and Clinic for Epilepsy Surgery; Schoen-Klinik Vogtareuth; 20 Krankenhausstrasse, D-83569, Vogtareuth, DeutschlandWith a few exceptions patients with tuberous sclerosis (TS) suffering from drug-resistant epilepsies have potentially epileptogenic lesionswithin both hemispheres. Until one decade ago in general such a constellation was an xclusion criteria for considerations with respect to epilepsy surgery. However experience has shown that it is not so rare to find patients in whom over the ears seizures are generated from just one single focus and that these patients can be good candidates for epilepsy surgery. Almost revolutionary was the further evelopment: multi-step procedures in patients with bilateral epileptogenic lesions – with promising results in terms of postoperative seizure outcome. Also, with increasing experience, it becomes more and more possible to differentiate already non-invasively which lesions could be epileptogenic and which are rather not the source of the seizures. The most important achievement of epilepsy surgery in TS however is that in selected cases early surgical intervention is able to prevent severe mental retardations, which are often the main burden for families who have members with this peculiar disease.https://rjdn.abvpress.ru/jour/article/view/46tuberous sclerosisepilepsymental retardationepilepsy surgery |
| spellingShingle | Hans Holthausen Tom Pieper Hans Eitel Manfred Kudernatsch EPILEPSY SURGERY IN PATIENTS WITH TUBEROUS SCLEROSIS Русский журнал детской неврологии tuberous sclerosis epilepsy mental retardation epilepsy surgery |
| title | EPILEPSY SURGERY IN PATIENTS WITH TUBEROUS SCLEROSIS |
| title_full | EPILEPSY SURGERY IN PATIENTS WITH TUBEROUS SCLEROSIS |
| title_fullStr | EPILEPSY SURGERY IN PATIENTS WITH TUBEROUS SCLEROSIS |
| title_full_unstemmed | EPILEPSY SURGERY IN PATIENTS WITH TUBEROUS SCLEROSIS |
| title_short | EPILEPSY SURGERY IN PATIENTS WITH TUBEROUS SCLEROSIS |
| title_sort | epilepsy surgery in patients with tuberous sclerosis |
| topic | tuberous sclerosis epilepsy mental retardation epilepsy surgery |
| url | https://rjdn.abvpress.ru/jour/article/view/46 |
| work_keys_str_mv | AT hansholthausen epilepsysurgeryinpatientswithtuberoussclerosis AT tompieper epilepsysurgeryinpatientswithtuberoussclerosis AT hanseitel epilepsysurgeryinpatientswithtuberoussclerosis AT manfredkudernatsch epilepsysurgeryinpatientswithtuberoussclerosis |