Association of socioeconomic status with clinical characteristics, care quality and outcomes in patients undergoing transcatheter aortic valve implantation

Background: Socioeconomic status (SES) is an important determinant of healthcare outcomes in many settings, but few studies have evaluated the impact of SES among patients with aortic stenosis (AS). We sought to explore the association between SES and clinical characteristics, care quality and outco...

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Main Authors: Jennifer Zhou, Shane Nanayakkara, Rozanne Johnston, Ellen Gardner, Nay Min Htun, Sonny Palmer, Samer Noaman, Liam Guiney, David M. Kaye, Antony S. Walton, Dion Stub
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:International Journal of Cardiology: Heart & Vasculature
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352906724002276
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author Jennifer Zhou
Shane Nanayakkara
Rozanne Johnston
Ellen Gardner
Nay Min Htun
Sonny Palmer
Samer Noaman
Liam Guiney
David M. Kaye
Antony S. Walton
Dion Stub
author_facet Jennifer Zhou
Shane Nanayakkara
Rozanne Johnston
Ellen Gardner
Nay Min Htun
Sonny Palmer
Samer Noaman
Liam Guiney
David M. Kaye
Antony S. Walton
Dion Stub
author_sort Jennifer Zhou
collection DOAJ
description Background: Socioeconomic status (SES) is an important determinant of healthcare outcomes in many settings, but few studies have evaluated the impact of SES among patients with aortic stenosis (AS). We sought to explore the association between SES and clinical characteristics, care quality and outcomes among patients undergoing transcatheter aortic valve implantation (TAVI) for severe AS. Methods: Consecutive patients undergoing TAVI for severe AS at three hospitals between August 2008 and February 2023 were prospectively enrolled in a multicentre registry. Patients were stratified into SES quintiles using a census-derived index. Demographic, procedural, and outcomes data were retrospectively analysed. Results: A total of 2,462 patients underwent TAVI during the study period. Lower SES patients were younger than those of higher SES, had more comorbidities, and were less likely to have private health insurance or receive care in private hospitals. Compared to higher SES groups, lower SES patients presented with more advanced disease markers (lower aortic valve area, lower dimensionless index, increased pulmonary hypertension) and were more likely to undergo urgent TAVI, but faced longer wait times for elective TAVI. Despite these pre-procedural differences, mortality and complication rates were similar across SES groups. In multivariable analyses, SES was not an independent predictor of mortality or major adverse cardiovascular events (MACE) at 30 days or 12 months. Conclusions: SES did not independently predict mortality or MACE in patients undergoing TAVI for severe AS. However, disparities in pre-procedural characteristics and access barriers were identified, highlighting the need to address SES-related inequities in healthcare delivery.
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spelling doaj-art-7ad87f019ca5405e8f38c86de2cce0542025-08-20T02:07:01ZengElsevierInternational Journal of Cardiology: Heart & Vasculature2352-90672024-12-015510156110.1016/j.ijcha.2024.101561Association of socioeconomic status with clinical characteristics, care quality and outcomes in patients undergoing transcatheter aortic valve implantationJennifer Zhou0Shane Nanayakkara1Rozanne Johnston2Ellen Gardner3Nay Min Htun4Sonny Palmer5Samer Noaman6Liam Guiney7David M. Kaye8Antony S. Walton9Dion Stub10Department of Cardiology, Heart Centre, Alfred Health, Melbourne, Australia; School of Public Health and Preventive Medicine, Monash University, Melbourne, AustraliaDepartment of Cardiology, Heart Centre, Alfred Health, Melbourne, Australia; Monash-Alfred-Baker Centre for Cardiovascular Research, Monash University, Melbourne, Australia; Department of Cardiology, Cabrini Hospital, Malvern, AustraliaDepartment of Cardiology, Heart Centre, Alfred Health, Melbourne, AustraliaDepartment of Cardiology, Heart Centre, Alfred Health, Melbourne, AustraliaDepartment of Cardiology, Heart Centre, Alfred Health, Melbourne, Australia; Department of Cardiology, Cabrini Hospital, Malvern, AustraliaDepartment of Cardiology, Heart Centre, Alfred Health, Melbourne, Australia; Department of Medicine, The University of Melbourne, Melbourne, AustraliaDepartment of Cardiology, Heart Centre, Alfred Health, Melbourne, Australia; Department of Cardiology, Epworth Hospital, Richmond, AustraliaDepartment of Cardiology, Heart Centre, Alfred Health, Melbourne, AustraliaDepartment of Cardiology, Heart Centre, Alfred Health, Melbourne, Australia; Monash-Alfred-Baker Centre for Cardiovascular Research, Monash University, Melbourne, AustraliaDepartment of Cardiology, Heart Centre, Alfred Health, Melbourne, Australia; Monash-Alfred-Baker Centre for Cardiovascular Research, Monash University, Melbourne, Australia; Department of Cardiology, Epworth Hospital, Richmond, AustraliaDepartment of Cardiology, Heart Centre, Alfred Health, Melbourne, Australia; School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia; Monash-Alfred-Baker Centre for Cardiovascular Research, Monash University, Melbourne, Australia; Department of Cardiology, Cabrini Hospital, Malvern, Australia; Corresponding author at: Heart Centre, Phillip Block, Level 3, The Alfred Hospital, 55 Commercial Road, Melbourne, VIC 3004, Australia.Background: Socioeconomic status (SES) is an important determinant of healthcare outcomes in many settings, but few studies have evaluated the impact of SES among patients with aortic stenosis (AS). We sought to explore the association between SES and clinical characteristics, care quality and outcomes among patients undergoing transcatheter aortic valve implantation (TAVI) for severe AS. Methods: Consecutive patients undergoing TAVI for severe AS at three hospitals between August 2008 and February 2023 were prospectively enrolled in a multicentre registry. Patients were stratified into SES quintiles using a census-derived index. Demographic, procedural, and outcomes data were retrospectively analysed. Results: A total of 2,462 patients underwent TAVI during the study period. Lower SES patients were younger than those of higher SES, had more comorbidities, and were less likely to have private health insurance or receive care in private hospitals. Compared to higher SES groups, lower SES patients presented with more advanced disease markers (lower aortic valve area, lower dimensionless index, increased pulmonary hypertension) and were more likely to undergo urgent TAVI, but faced longer wait times for elective TAVI. Despite these pre-procedural differences, mortality and complication rates were similar across SES groups. In multivariable analyses, SES was not an independent predictor of mortality or major adverse cardiovascular events (MACE) at 30 days or 12 months. Conclusions: SES did not independently predict mortality or MACE in patients undergoing TAVI for severe AS. However, disparities in pre-procedural characteristics and access barriers were identified, highlighting the need to address SES-related inequities in healthcare delivery.http://www.sciencedirect.com/science/article/pii/S2352906724002276Aortic stenosisTranscatheter aortic valve implantationSocioeconomic statusOutcomesQuality of care
spellingShingle Jennifer Zhou
Shane Nanayakkara
Rozanne Johnston
Ellen Gardner
Nay Min Htun
Sonny Palmer
Samer Noaman
Liam Guiney
David M. Kaye
Antony S. Walton
Dion Stub
Association of socioeconomic status with clinical characteristics, care quality and outcomes in patients undergoing transcatheter aortic valve implantation
International Journal of Cardiology: Heart & Vasculature
Aortic stenosis
Transcatheter aortic valve implantation
Socioeconomic status
Outcomes
Quality of care
title Association of socioeconomic status with clinical characteristics, care quality and outcomes in patients undergoing transcatheter aortic valve implantation
title_full Association of socioeconomic status with clinical characteristics, care quality and outcomes in patients undergoing transcatheter aortic valve implantation
title_fullStr Association of socioeconomic status with clinical characteristics, care quality and outcomes in patients undergoing transcatheter aortic valve implantation
title_full_unstemmed Association of socioeconomic status with clinical characteristics, care quality and outcomes in patients undergoing transcatheter aortic valve implantation
title_short Association of socioeconomic status with clinical characteristics, care quality and outcomes in patients undergoing transcatheter aortic valve implantation
title_sort association of socioeconomic status with clinical characteristics care quality and outcomes in patients undergoing transcatheter aortic valve implantation
topic Aortic stenosis
Transcatheter aortic valve implantation
Socioeconomic status
Outcomes
Quality of care
url http://www.sciencedirect.com/science/article/pii/S2352906724002276
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