Modified Saengmaeksan, an herbal formula containing six herbs, improves hypertension through RhoA/Rho kinase-mediated vasorelaxation

Modified Saengmaeksan, an herbal formula containing six herbs, improves hypertension through RhoA/Rho kinase-mediated vasorelaxation

Background: Saengmaeksan is a traditional herbal formula used in Korean medicine. We composed a modified formula based on Saengmaeksan (mSMS) with Puerariae Radix, Platycodonis Radix, Liriopis seu Ophiopogonis Tuber, Schisandrae Fructus, Coicis Semen, and Dioscoreae Rhizoma to investigate its in viv...

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Bibliographic Details
Main Authors: Young Mi Seok, Hye-Lin Kim, Hyo In Kim, Hobin Moon, Yohan Han, Eun Sang Cho, Hyun Hee Leem, Hyo Jung Kim, Sujin Shin, Se-Jin Kim, Jin Ki Jung, Wei Huang, Kyung Oh Jung, Doo Suk Lee, Sung Giu Jin, Hyunwoo Kim, Changsop Yang, Kyungjin Lee, Jinbong Park
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:Integrative Medicine Research
Subjects:
Angiotensin II receptor type 1
Herbal medicine
Hypertension
Reactive oxygen species
RhoA/Rho kinase pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2213422025000873
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