Primary Ewing's Sarcoma of Frontoparietal Bone with Major Soft Tissue Extension: An Unusual Presentation and Review of the Literature

An 11-year-old girl presented with progressively increasing swelling in scalp of 8-month duration with no neurological deficit. Local examination showed a hard swelling that seemed to be arising from frontal bone. General and systemic examination was normal. MRI revealed a well-defined lytic lesion...

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Main Authors: Anshu Gupta, Sachin Bansal, Sujata Chaturvedi
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2012/713836
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author Anshu Gupta
Sachin Bansal
Sujata Chaturvedi
author_facet Anshu Gupta
Sachin Bansal
Sujata Chaturvedi
author_sort Anshu Gupta
collection DOAJ
description An 11-year-old girl presented with progressively increasing swelling in scalp of 8-month duration with no neurological deficit. Local examination showed a hard swelling that seemed to be arising from frontal bone. General and systemic examination was normal. MRI revealed a well-defined lytic lesion in left frontoparietal bone with a subgaleal component. The patient was operated upon and excision of tumor with reconstruction of skull was done. Histopathological examination showed a monomorphic small round cell tumor of bone infiltrating into the subcutaneous tissue. Immunohistochemical stain showed diffuse immunopositivity for MIC-2 in tumor cells, thus final diagnosis of Ewing’s sarcoma was made. The patient was kept for follow up for 3 months and had no symptoms.
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spelling doaj-art-7ab83c0ef1a64fd2be5eba165a545bbb2025-08-20T02:07:38ZengWileyCase Reports in Pathology2090-67812090-679X2012-01-01201210.1155/2012/713836713836Primary Ewing's Sarcoma of Frontoparietal Bone with Major Soft Tissue Extension: An Unusual Presentation and Review of the LiteratureAnshu Gupta0Sachin Bansal1Sujata Chaturvedi2Department of Pathology, Institute of Human Behavior and Allied Sciences, Dilshad Garden, Delhi 95, IndiaDepartment of Pathology, Institute of Human Behavior and Allied Sciences, Dilshad Garden, Delhi 95, IndiaDepartment of Pathology, Institute of Human Behavior and Allied Sciences, Dilshad Garden, Delhi 95, IndiaAn 11-year-old girl presented with progressively increasing swelling in scalp of 8-month duration with no neurological deficit. Local examination showed a hard swelling that seemed to be arising from frontal bone. General and systemic examination was normal. MRI revealed a well-defined lytic lesion in left frontoparietal bone with a subgaleal component. The patient was operated upon and excision of tumor with reconstruction of skull was done. Histopathological examination showed a monomorphic small round cell tumor of bone infiltrating into the subcutaneous tissue. Immunohistochemical stain showed diffuse immunopositivity for MIC-2 in tumor cells, thus final diagnosis of Ewing’s sarcoma was made. The patient was kept for follow up for 3 months and had no symptoms.http://dx.doi.org/10.1155/2012/713836
spellingShingle Anshu Gupta
Sachin Bansal
Sujata Chaturvedi
Primary Ewing's Sarcoma of Frontoparietal Bone with Major Soft Tissue Extension: An Unusual Presentation and Review of the Literature
Case Reports in Pathology
title Primary Ewing's Sarcoma of Frontoparietal Bone with Major Soft Tissue Extension: An Unusual Presentation and Review of the Literature
title_full Primary Ewing's Sarcoma of Frontoparietal Bone with Major Soft Tissue Extension: An Unusual Presentation and Review of the Literature
title_fullStr Primary Ewing's Sarcoma of Frontoparietal Bone with Major Soft Tissue Extension: An Unusual Presentation and Review of the Literature
title_full_unstemmed Primary Ewing's Sarcoma of Frontoparietal Bone with Major Soft Tissue Extension: An Unusual Presentation and Review of the Literature
title_short Primary Ewing's Sarcoma of Frontoparietal Bone with Major Soft Tissue Extension: An Unusual Presentation and Review of the Literature
title_sort primary ewing s sarcoma of frontoparietal bone with major soft tissue extension an unusual presentation and review of the literature
url http://dx.doi.org/10.1155/2012/713836
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AT sujatachaturvedi primaryewingssarcomaoffrontoparietalbonewithmajorsofttissueextensionanunusualpresentationandreviewoftheliterature