Primary diffuse large B-cell lymphoma of the central nervous system (case report and literature review)

The central nervous system (CNS) involvement in patients with non-Hodgkin’s lymphomas is not uncommon, especially in children with mature B-cells lymphomas, unlike the primary CNS lymphoma (PCNSL). PCNSL is a rare extranodal form of NHL that occurs only in the CNS – in the brain, spinal cord, mening...

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Bibliographic Details
Main Authors: K. A. Komratova, Yu. G. Abugova, S. S. Ozerov, D. S. Abramov, G. V. Tereshchenko, N. V. Myakova
Format: Article
Language:Russian
Published: ABV-press 2017-04-01
Series:Онкогематология
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Online Access:https://oncohematology.abvpress.ru/ongm/article/view/227
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Summary:The central nervous system (CNS) involvement in patients with non-Hodgkin’s lymphomas is not uncommon, especially in children with mature B-cells lymphomas, unlike the primary CNS lymphoma (PCNSL). PCNSL is a rare extranodal form of NHL that occurs only in the CNS – in the brain, spinal cord, meninges, in the eyes, and not extending beyond CNS. Its frequency in adults is 1–2 % of lymphomas and 5 % of all CNS tumors. Data on prevalence in childhood are not available, limited to some case reports. This article presents a literature review about PCNSL diagnosis and treatment and case report of such lymphoma with intraspinal lesion in 11 years old child.
ISSN:1818-8346
2413-4023